Evidence map›Paper›PMID 33904234›Full record

ArticleExperimental physiology2022

Carotid stiffness, intima-media thickness and aortic augmentation index among adults with SARS-CoV-2.

Rachel E Szeghy, Valesha M Province, Nina L Stute, Marc A Augenreich, Laurel K Koontz, Jonathon L Stickford, Abigail S L Stickford, Stephen M Ratchford

Open access · bronzeAbstract read
In one paragraph

Article in Experimental physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 81 citations in OpenAlex.

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  14. Value ofInternational journal of cardiology. Heart & vasculature · 2024
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  15. Review
  16. The gut microbiome as a modulator of arterial function and age-related arterial dysfunction.American journal of physiology. Heart and circulatory physiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rachel E SzeghyDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.ORCID 0000-0001-6822-6186
Valesha M ProvinceDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.
Nina L StuteDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.ORCID 0000-0001-8213-638X
Marc A AugenreichDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.ORCID 0000-0002-0719-8799
Laurel K KoontzDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.
Jonathon L StickfordDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.
Abigail S L StickfordDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.
Stephen M RatchfordDepartment of Health & Exercise Science, Appalachian State University, Boone, North Carolina, USA.ORCID 0000-0002-6300-7600
Appalachian State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NEW

findingsWhat is the central question of this study? We sought to investigate whether carotid stiffness, carotid intima-media thickness and the aortic augmentation index are altered in young adults 3-4 weeks after contraction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with young healthy adults. What is the main finding and its importance? We found that carotid stiffness, Young's modulus and the aortic augmentation index were greater in young adults who tested positive for SARS-CoV-2 compared with healthy young adults. These findings provide additional evidence for detrimental effects of SARS-CoV-2 on young adult vasculature, which might have implications for cardiovascular health. ABSTRACT: Contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been observed to cause decrements in vascular function of young adults. However, less is known about the impact of SARS-CoV-2 on arterial stiffness and structure, which might have additional implications for cardiovascular health. The purpose of this study was to assess the carotid artery stiffness and structure using ultrasound and the aortic augmentation index (AIx) using applanation tonometry in young adults after they tested positive for SARS-CoV-2. We hypothesized that carotid artery stiffness, carotid intima-media thickness (cIMT) and aortic AIx would be elevated in young adults with SARS-CoV-2 compared with healthy young adults. We evaluated 15 young adults (six male and nine female; 20 ± 1 years of age; body mass index, 24 ± 3 kg m

Indexed as

COVID-19Vascular StiffnessCarotid ArteriesCarotid Intima-Media ThicknessCross-Sectional StudiesFemaleHumansInfantMaleSARS-CoV-2Young Adultaortic augmentation indexcarotid stiffnessCOVID-19intima-media thicknessSARS-CoV-2

Identifiers

PMID33904234
PMCPMC8239784
OpenAlexW3158274933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.