Evidence map›Paper›PMID 33904156›Full record

ArticleJournal of the American Geriatrics Society2021

Ambient fine particulate matter exposure and incident mild cognitive impairment and dementia.

Kevin J Sullivan, Xinhui Ran, Fan Wu, Chung-Chou H Chang, Ravi Sharma, Erin Jacobsen, Sarah Berman, Beth E Snitz, Akira Sekikawa, Evelyn O Talbott and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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  18. The Epidemiological and Toxicological Intersection of Air Pollution and Dementia.Reviews of environmental contamination and toxicology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kevin J SullivanDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9147-0988
Xinhui RanDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Fan WuDepartment of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Chung-Chou H ChangDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Ravi SharmaDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Erin JacobsenDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sarah BermanDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Beth E SnitzDepartment of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Akira SekikawaDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Evelyn O TalbottDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Mary GanguliDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · US

Funding

Mild Cognitive Impairment: A Prospective Community StudyR01AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2005 to 2020
$27.1M
Mild Cognitive Impairment: A Prospective Community StudyR37AG023651 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Carmen Andreescu, MARY GANGULI · 2021 to 2026
$18.2M
TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
Alzheimer neuroimaging-biomarkers in pre-clinical cognitive decline from a population-based studyR01AG052521 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SNITZ, BETH · 2016 to 2020
$3.3M
NIA NIH HHS R01 AG023651NIA NIH HHS R01 AG052521NIA NIH HHS R37 AG023651NIA NIH HHS T32 AG000181
6 · The paper itself

Abstract

BACKGROUND/

objectivePoor air quality is implicated as a risk factor for cognitive impairment and dementia. Few studies have examined these associations longitudinally in well-characterized population-based cohorts with standardized annual assessment of both mild cognitive impairment (MCI) and dementia. We investigated the association between estimated ambient fine particulate matter (PM SETTING/

participantsAdults aged 65+ years in a population-based cohort (n = 1572). MEASUREMENTS: Census tract level PM

designWe estimated ambient PM

resultsModeling estimated single-year exposure, each 1 μg/m

conclusionsHigher estimated ambient PM

Indexed as

AgedAged, 80 and overAir PollutionBayes TheoremCausalityCognitive DysfunctionDementiaFemaleHumansIncidenceLongitudinal StudiesMaleParticulate MatterPennsylvaniaRisk AssessmentParticulate Matterair pollutioncognitive impairmentdementiaepidemiologyfine particulate matter

Identifiers

PMID33904156
PMCPMC8373708
OpenAlexW3159900189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.