ArticleAging clinical and experimental research2021
Age-related composition changes in swallowing-related muscles: a Dixon MRI study.
Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 18 citations in OpenAlex.
- The Relationship between Swallowing Muscle Mass and Tongue Muscle Strength and Endurance in Head and Neck Cancer Patients.Dysphagia · 2026Article
- Association Between Chin-Tuck-Generated Force and Sarcopenia in Community-Dwelling Older Adults: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Sex difference in oral frailty Among older hospitalized cancer patients: a cross-sectional survey in taizhou, China.Frontiers in dental medicine · 2026Article
- Relationship Between Swallowing Frequency and Swallowing-Related Muscle Mass in Older Adults.Journal of oral rehabilitation · 2026Article
- Chewing ability and its associated factors in maintenance hemodialysis patients: a cross-sectional study.BMC oral health · 2025Article
- Head Lifting Strength is Associated with Pharyngeal Residuals in Older Inpatients with Suspected Dysphagia.Dysphagia · 2025Article
- Reliability and Validity of Measuring the Strength of the Chin-Tuck Maneuver in Community-Dwelling Older Adults as a Means of Evaluating Swallowing-Related Muscle Strength.Geriatrics (Basel, Switzerland) · 2024Article
- MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle.Journal of imaging · 2024Review
- A new computed tomography-based approach to quantify swallowing muscle volume by measuring tongue muscle area in a single slice.Journal of cachexia, sarcopenia and muscle · 2024Article
- Swallowing muscle mass contributes to post-stroke dysphagia in ischemic stroke patients undergoing mechanical thrombectomy.Journal of cachexia, sarcopenia and muscle · 2024Article
- Muscle MRI in Patients With Oculopharyngeal Muscular Dystrophy: A Longitudinal StudyNeurology · 2024Article
- The Use of MR-Guided Radiation Therapy for Head and Neck Cancer and Recommended Reporting Guidance.Seminars in radiation oncology · 2024Review
- Sarcopenic Dysphagia and Simplified Rehabilitation Nutrition Care Process: An Update.Annals of rehabilitation medicine · 2023Article
- Novel methodology to quantify dehydration in head and neck cancer radiotherapy using DIXON MRI.Journal of medical radiation sciences · 2022Article
- Sarcopenic Dysphagia, Malnutrition, and Oral Frailty in Elderly: A Comprehensive Review.Nutrients · 2022Review
- Phase angle and overhydration are associated with post-extubating dysphagia in patients with COVID-19 discharged from the ICU.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022Article
- Clinical determinants and neural correlates of presbyphagia in community-dwelling older adults.Frontiers in aging neuroscience · 2022Article
- Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDysphagia is considered a social problem in the super-aging society. However, age-related changes in swallowing-related muscles have not been fully deciphered.
aimsWe aimed to identify intramuscular fatty infiltration and muscle atrophy in multiple swallowing-related muscles on magnetic resonance imaging (MRI). Moreover, an appropriate muscle strength parameter for the evaluation of swallowing-related muscle mass was examined.
methodsWe analyzed the Dixon MRI results of 20 elderly and 20 young adults without head and neck cancer, stroke, neuromuscular disease, or whole-body sarcopenia to evaluate intramuscular fatty infiltration (IMF) and lean muscle mass (LMM) in the tongue, geniohyoid, and pharyngeal muscles. The pharyngeal lumen size was also assessed. Tongue pressure, jaw-opening strength, occlusal force, and head-lifting strength were evaluated within a week before and after MRI.
resultsAging significantly affected the IMF of the swallowing-related muscles, and the tongue muscle was most affected, followed by the pharyngeal muscle and then the geniohyoid muscle. Only the LMM of the geniohyoid muscle significantly decreased with aging. The pharyngeal lumen size did not significantly differ between the elderly and young participants, and only tongue pressure was significantly correlated with tongue, geniohyoid, and pharyngeal muscle mass.
conclusionsIMF is primarily associated with age-related composition changes in swallowing-related muscles, and it is commonly observed in the tongue and pharyngeal muscles. The geniohyoid muscle is more at risk of muscle atrophy rather than fatty infiltration. In addition, tongue pressure can be a parameter for the evaluation of swallowing-related muscle mass.
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