Evidence map›Paper›PMID 33903935›Full record

ArticleJournal of molecular modeling2021

A general RNA force field: comprehensive analysis of energy minima of molecular fragments of RNA.

Yongna Yuan, Matthew J L Mills, Zhuangzhuang Zhang, Yan Ma, Chunyan Zhao, Wei Su

Abstract read
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In one paragraph

Article in Journal of molecular modeling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yongna YuanSchool of Information Science & Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China. yuanyn@lzu.edu.cn.ORCID http://orcid.org/0000-0003-1141-6098
Matthew J L Mills3M Corporate Research Analytical Laboratory, Saint Paul, MN, 55114, USA.
Zhuangzhuang ZhangSchool of Information Science & Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
Yan MaSchool of Information Science & Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.
Chunyan ZhaoSchool of Pharmacy, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China. zhaochy07@lzu.edu.cn.
Wei SuSchool of Information Science & Engineering, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, 730000, China.

Funding

Fundamental Research Funds for the Central Universities lzujbky-2019-cd05National Natural Science Foundation of China 21503101National Natural Science Foundation of China 81973786Science Foundation of Guangxi AA17204096Science Foundation of Guangxi AD16380076
6 · The paper itself

Abstract

Force fields are actively used to study RNA. Development of accurate force fields relies on a knowledge of how the variation of properties of molecules depends on their structure. Detailed scrutiny of RNA's conformational preferences is needed to guide such development. Towards this end, minimum energy structures for each of a set of 16 small RNA-derived molecules were obtained by geometry optimization at the HF/6-31G(d,p), B3LYP/apc-1, and MP2/cc-pVDZ levels of theory. The number of minima computed for a given fragment was found to be related to both its size and flexibility. Atomic electrostatic multipole moments of atoms occurring in the [HO-P(O

Indexed as

Models, MolecularComputational ChemistryNucleic Acid ConformationQuantum TheoryRNARNAConformational analysisForce fieldMultipole momentsQuantum chemical topologyRNA

Identifiers

PMID33903935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.