Evidence map›Paper›PMID 33903933›Full record

ArticleSurgical endoscopy2022

A new designed self-expandable metal stent for the management of benign radiotherapy-induced hypopharyngeal or cervical esophageal strictures.

Massimo Conio, Rosa Angela Filiberti, Peter D Siersema, Raffaele Manta, Sabrina Blanchi, Antonella De Ceglie

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Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Massimo ConioDepartment of Gastroenterology, Sanremo General Hospital, Sanremo, IM, Italy. mxconio@tim.it.
Rosa Angela FilibertiClinical Epidemiology Unit, Ospedale Policlinico San Martino, Genova, Italy.
Peter D SiersemaDepartment. of Gastroenterology and Hepatology (Route 763), Radboud University Medical Center, Nijmegen, The Netherlands.
Raffaele MantaGastroenterology and Digestive Endoscopy, General Hospital, 06129, Perugia, Italy.
Sabrina BlanchiDepartment of Gastroenterology, Sanremo General Hospital, Sanremo, IM, Italy.
Antonella De CeglieDepartment of Gastroenterology, Sanremo General Hospital, Sanremo, IM, Italy.ORCID 0000-0002-2412-7220
Ospedale di Sanremo · ITAzienda Ospedaliera di Perugia · ITOspedale Policlinico San Martino · ITRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe management of patients with hypopharyngeal or cervical esophageal refractory benign strictures (RBS) after surgery and radiotherapy ± chemotherapy for laryngeal cancer is challenging. We aimed to assess the long-term efficacy and safety of a new designed fully covered SEMS in these patients.

methodsWe reviewed the results of a prospectively collected database of 40 consecutive patients with dysphagia due to RBS of the cervical esophagus or hypopharynx after surgery and radiotherapy with or without chemotherapy for laryngeal cancer, unfit for surgery, referred in two tertiary-care endoscopic centers from June 2005 to December 2018. All of them were treated with placement of a Niti-S Conio cervical stent.

resultsAfter placement of the first stent, dysphagia improved in all patients. The total number of adverse events was 35 out of a total of 299 procedures (11.7%): 25 (8.4%) stent migrations, 6 (2%) tumor overgrowth, 3 severe pain and 1 pharyngo-cutaneous fistula. Stents were periodically changed. In only one patient with a cervical esophageal stricture the stent was definitively removed after 7 sessions of stent placement because of stricture resolution. Patients were followed-up for a median of 11.6 months and a significant improvement in dysphagia was reported in all patients (p < 0.001).

conclusionsThe use of this conformable, small caliber new designed Niti-S stent, exchanged periodically, appeared safe and permitted durable oral intake in patients with difficult-to-treat hypopharyngeal or cervical esophagus strictures, avoiding the need for periodic dilations.

Indexed as

Deglutition DisordersEsophageal StenosisLaryngeal NeoplasmsConstriction, PathologicHumansHypopharynxStentsTreatment OutcomeCervical stentEsophagusHypopharynxRefractory benign strictures

Identifiers

PMID33903933
OpenAlexW3159187747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.