ArticleScientific reports2021
Elongation of the disc-fovea distance and retinal vessel straightening in high myopia in a 10-year follow-up of the Beijing eye study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Associations between Retinal Nerve Fiber Layer Thickness, Axial Length, and Generation in the 2-Continent Eye Study.Ophthalmology science · 2026Article
- Association Between Extrafoveal Paravascular Retinoschisis and Central Retinal Vessel Trunk Dragging in High Myopia.Investigative ophthalmology & visual science · 2026Article
- Interocular asymmetry and ocular biometric patterns in pediatric high myopia: implications for early risk stratification.Frontiers in medicine · 2026Article
- Artificial intelligence assisted quantitative analysis of fundus structural and vascular alterations reveals fundus tessellation as a robust biomarker of myopia severity.Frontiers in cell and developmental biology · 2026Article
- Strong association between decreased stroma in Sattler's layer and high myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Changes of the Optic Nerve Head and Macula in High Myopia in a 10-Year Follow-Up: The Beijing Eye Study.Investigative ophthalmology & visual science · 2025Article
- Glaucomatous, Glaucoma-Like, and Non-Glaucomatous Optic Neuropathy in High Myopia: The Two-Continent Study.Investigative ophthalmology & visual science · 2025Article
- Independent Effects of Axial Length and Intraocular Pressure on the Highly Myopic Optic Nerve Head.Investigative ophthalmology & visual science · 2025Article
- Myopic-Net: Deep Learning-Based Direct Identification of Myopia Onset and Progression.Translational vision science & technology · 2025Article
- Interplay Between γ-Zone Peripapillary Atrophy and Optic Disc Parameters in Central Visual Field Impairment in Highly Myopic Eyes.Investigative ophthalmology & visual science · 2025Article
- Convolutional Neural Network-Based Prediction of Axial Length Using Color Fundus Photography.Translational vision science & technology · 2024Article
- Retinal Changes From Hyperopia to Myopia: Not All Diopters Are Created Equal.Investigative ophthalmology & visual science · 2024Article
- Multifunctional adaptive optics optical coherence tomography allows cellular scale reflectometry, polarimetry, and angiography in the living human eye.Biomedical optics express · 2024Article
- Retinal Artery Angles in High Axial Myopia and Its Relationship With Visual Function.Translational vision science & technology · 2023Article
- High myopia as risk factor for the 10-year incidence of open-angle glaucoma in the Beijing Eye Study.The British journal of ophthalmology · 2023Observational
- IMI-Nonpathological Human Ocular Tissue Changes With Axial Myopia.Investigative ophthalmology & visual science · 2023Article
- Macular outer nuclear layer, ellipsoid zone and outer photoreceptor segment band thickness, axial length and other determinants.Scientific reports · 2023Article
- Anatomic Peculiarities Associated with Axial Elongation of the Myopic Eye.Journal of clinical medicine · 2023Review
- Choroidal shift in myopic eyes in the 10-year follow-up Beijing eye study.Scientific reports · 2021Article
- Sectoral Changes in Neuroretinal Rim Pallor Across Refractive Error.Ophthalmology scienceArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess changes in the disc-fovea distance (DFD) in highly myopic eyes in a 10-year population-based follow-up study. The case control study included all highly myopic eyes (myopic refractive error ≥ - 6.0 diopters or axial length ≥ 26.0 mm) and a randomized group of non-highly myopic eyes examined in the population-based Beijing Eye Study 2001 and 2011. Using fundus photographs and optical coherence tomographic images, we assessed changes in DFD, parapapillary gamma zone, angle kappa (angle between the temporal arterial arcades), and course of papillo-macular retinal vessels. The study included 89 highly myopic eyes and 86 non-highly myopic eyes. DFD elongation, gamma zone widening, angle kappa decrease and straightening of papillo-macular retinal vessels were detected more often (all P < 0.001) in the highly myopic group than in the non-highly myopic group (63/89 versus 9/86;75/89 versus 18/86;61/89 versus 9/86; and 58/89 versus 7/86,respectively). Gamma zone enlargement, angle kappa reduction and papillo-macular retinal vessel straightening were significantly (all P < 0.001) associated with DFD elongation. The length of macular Bruch's membrane on the disc-fovea line and the vertical distance between the temporal arterial arcade did not change during follow-up. DFD elongation (10-year incidence 70.8% in highly myopic eyes) was associated with gamma zone enlargement, while macular Bruch's membrane length remained unchanged. It supports the notion of a temporal shift of an otherwise stable posterior Bruch's membrane in axially elongated eyes. Straightening of the papillo-macular vessels with increasing gamma zone width suggests a coincident stretching of the papillo-macular retinal nerve fibers and inner limiting membrane.
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