Trial reportScientific reports2021
Intraocular pressure and choroidal thickness postural changes in multiple system atrophy and Parkinson's disease.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Detection of macular and peripheral ocular microvascular changes after carotid artery revascularization using widefield SS-OCTA.Frontiers in medicine · 2025Article
- Effects of a 24-week yoga intervention on choriocapillaris density in Parkinson's disease.Clinical parkinsonism & related disorders · 2025Article
- Effects of Alpha-Lytic Therapy Withdrawal on Choroidal Parameters in Intraoperative Floppy Iris Syndrome High-Risk Patients.Journal of clinical medicine · 2024Article
- Optic nerve head neurovascular assessments in patients with schizophrenia: A cross-sectional study.Health science reports · 2024Article
- The Correlation between Retinal and Choroidal Thickness with Age-Related White Matter Hyperintensities in Progressive Supranuclear Palsy.Journal of clinical medicine · 2023Article
- Evaluation of Tropicamide-Phenylephrine Mydriatic Eye Drop Instillation on Choroidal Thickness.Journal of clinical medicine · 2023Article
- Intraocular Pressure Variations in Postural Changes: Comparison between Obese and Non-Obese Controls.Journal of clinical medicine · 2023Article
- Does Subretinal Fluid Influence Choroidal Thickness (ChT) and Structure in Preeclampsia with Serous Retinal Detachment? Comment on Fukui et al. Changes in Choroidal Thickness and Structure in Preeclampsia with Serous Retinal Detachment.Journal of clinical medicine · 2023Article
- Choroidal Thickness Measurements in the Case of Diabetic Macular Edema. Comment on Amjad et al. Choroidal Thickness in Different Patterns of Diabetic Macular Edema.Journal of clinical medicine · 2023Article
- Article
- Comment on Naranjo-Bonilla et al. Retinal and Choroidal Effects of Continuous Positive Airway Pressure as Treatment for Sleep Apnea: Results at 12 Months.International journal of environmental research and public health · 2023Article
- Choroidal Thickness and Retinal Vein Occlusions [Letter].Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Editorial: Optical coherence tomography and OCT angiography examination in systemic diseases.Frontiers in medicine · 2023Article
- Herbal and Natural Treatments for the Management of the Glaucoma: An Update.BioMed research international · 2023Review
- OCT angiography indices and the choroidal vascularity index in wild-type transthyretin (TTR) amyloidosis (ATTRwt).Frontiers in medicine · 2023Article
- Intraocular Pressure Measurements in Standing, Sitting, and Supine Position: Comparison between Tono-Pen Avia and Icare Pro Tonometers.Journal of clinical medicine · 2022Article
- Seasonal Variation in Diurnal Rhythms of the Human Eye: Implications for Continuing Ocular Growth in Adolescents and Young Adults.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate intraocular pressure (IOP) and choroidal thickness (ChT) postural changes in multiple system atrophy (MSA), Parkinson's disease (PD) patients and healthy controls (HC). 20 MSA patients, 21 PD patients and 14 HC, were examined. All subjects underwent a complete examination, including corneal thickness, ChT, IOP and axial length (AL) measurements. IOP measurement was performed in supine, sitting, and standing positions, whereas ChT in sitting and standing positions. Supine to standing IOP variations were significantly higher in MSA vs PD(p = 0.01) and in MSA vs HC (p < 0.0001), whereas no significant differences were observed between PD and HC (p = 0.397). Mean sub-foveal ChT in MSA was 240 ± 92 μm in sitting position, and 215 ± 94 μm in standing position with a significant reduction (p = 0.008). Mean sub-foveal ChT in PD was 258 ± 79 μm in sitting position, and 259 ± 76 μm in standing position (p = 0.887). In HC it was 244 ± 36 μm in sitting position, and 256 ± 37 μm in standing position with a significant increase (p = 0.007). The significant IOP and ChT postural changes can be considered additional hallmarks of autonomic dysfunction in MSA and further studies are needed to consider them as biomarkers in the differential diagnosis with PD.
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