Evidence map›Paper›PMID 33903221›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Local and CNS-Wide Astrocyte Intracellular Calcium Signaling Attenuation

Xinzhu Yu, Stefanie L Moye, Baljit S Khakh

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Subicular Astrocytes Govern Seizure-Impaired Fear Memory.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Astrocytes in Rodent Anxiety-Related Behavior: Role of Calcium and Beyond.International journal of molecular sciences · 2025
    Review
  15. Astrocyte Calcium Signaling.Cold Spring Harbor perspectives in biology · 2024
    Review
  16. Microglial P2YNeuron · 2024
    Article
  17. Article
  18. Article
  19. Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  20. Astrocyte-specific CaBiochemistry and cell biology = Biochimie et biologie cellulaire · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Xinzhu YuDepartment of Physiology bkhakh@mednet.ucla.edu xinzhuyu@illinois.edu.ORCID https://orcid.org/0000-0003-1244-0110
Stefanie L MoyeDepartment of Physiology.
Baljit S KhakhDepartment of Physiology bkhakh@mednet.ucla.edu xinzhuyu@illinois.edu.
Czech Academy of Sciences, Institute of Physiology · CZUniversity of California, Los Angeles · USUniversity of Illinois Urbana-Champaign · US

Funding

Fundamental astrocyte biology in intact neural circuitsR35NS111583 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Baljit Khakh · 2019 to 2026
$7.9M
Integrative Center for Neurogenetics and Neurogenomics - OverallP30NS062691 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ESKIN, ELEAZAR · 2009 to 2018
$7.4M
UCLA Center for Translational Research in Neurodevelopment: UC-TRaNU54HD087101 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2016 to 2020
$6.5M
Astrocyte branchlet dysfunction as an early step in brain disordersDP1MH104069 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KHAKH, BALJIT · 2013 to 2017
$3.9M
New tools to target, identify and characterize astrocytes in the adult nervous systemR01DA047444 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRADINARU, VIVIANA, KHAKH, BALJIT · 2018 to 2020
$3.3M
NICHD NIH HHS U54 HD087101NIDA NIH HHS R01 DA047444NIMH NIH HHS DP1 MH104069NINDS NIH HHS P30 NS062691NINDS NIH HHS R35 NS111583
6 · The paper itself

Abstract

Astrocytes exist throughout the CNS and affect neural circuits and behavior through intracellular Ca

Indexed as

AnimalsAstrocytesBrainCalcium SignalingFemaleGene Knock-In TechniquesMaleMiceMice, Inbred C57BLAldh1l1-Cre/ERT2astrocytecalciumstriatum

Identifiers

PMID33903221
PMCPMC8260243
OpenAlexW3157175540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.