Evidence map›Paper›PMID 33903141›Full record

ArticleBMJ open2021

Death of a parent during childhood and blood pressure in youth: a population-based cohort study of Swedish men.

Hua Chen, Tomas Hemmingsson, Imre Janszky, Mikael Rostila, Yvonne Forsell, Linghui Meng, Yajun Liang, Krisztina D László

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Hua ChenDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden hua.chen@ki.se.ORCID 0000-0002-4884-3360
Tomas HemmingssonDepartment of Public Health Sciences, Stockholm University, Stockholm, Sweden.
Imre JanszkyDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Mikael RostilaDepartment of Public Health Sciences, Stockholm University, Stockholm, Sweden.
Yvonne ForsellDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Linghui MengDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Yajun LiangDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Krisztina D LászlóDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-4695-477X
Karolinska Institutet · SEStockholm University · SENorwegian University of Science and Technology · NOStockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCompelling evidence suggests that childhood adversities are associated with an increased risk of hypertension in middle age and old age. The link between childhood adversities and blood pressure in youth is less clear. In this cohort study, we examined the association between death of a parent during childhood and blood pressure in early adulthood in men.

settingSweden.

participantsWe studied 48 624 men born in 1949-1951 who participated in the compulsory military conscription in 1969/1970 in Sweden. Information on death of a parent during childhood was obtained from population-based registers. Information on covariates was obtained from the questionnaire and the clinical examination completed at conscription and from population-based registers. OUTCOME MEASURES: Blood pressure was measured at conscription according to standard procedures.

resultsThe multivariable least square means of systolic and diastolic blood pressure did not differ between bereaved (128.25 (127.04-129.46) and 73.86 (72.89-74.84) mm Hg) and non-bereaved study participants (128.02 (126.86-129.18) and 73.99 (73.06-74.93) mm Hg). Results were similar when considering the cause of the parent's death, the gender of the deceased parent or the child's age at loss. Loss of a parent in childhood tended to be associated with an increased hypertension risk (OR and 95% CI: 1.10 (1 to 1.20)); the association was present only in case of natural deaths.

conclusionWe found no strong support for the hypothesis that stress following the loss of a parent during childhood is associated with blood pressure or hypertension in youth in men.

Indexed as

Parental DeathParentsAdolescentAdultAgedBlood PressureChildCohort StudiesHumansMaleMiddle AgedSwedenepidemiologyhypertensionmental health

Identifiers

PMID33903141
PMCPMC8076918
OpenAlexW3157215527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.