ReviewEvidence-based mental health2021
WHO mental health gap action programme (mhGAP) intervention guide: updated systematic review on evidence and impact.
Review in Evidence-based mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
131 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Persuasive Systems Design Features of Smartphone Apps for Psychosis: Systematic Review.JMIR human factors · 2026Pooled it
- Effects of Integrated Care Approaches to Address Co-occurring Depression and Diabetes: A Systematic Review and Meta-analysis.Diabetes care · 2024Pooled it
- The Effectiveness and Feasibility of Psychological Interventions for Populations Under Ongoing Threat: A Systematic Review.Trauma, violence & abuse · 2024Pooled it
- Exploring Heterogeneity in perinatal depression: a comprehensive review.BMC psychiatry · 2023Pooled it
- Educational and Training Interventions Aimed at Healthcare Workers in the Detection and Management of People With Mental Health Conditions in South and South-East Asia: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Trial
- Mom Supporting Mom: Effective Peer Support Intervention for Women with Postpartum Psychological Distress.Psychosocial intervention · 2025Trial
- An App-Based WHO Mental Health Guide for Depression Detection: A Cluster Randomized Clinical Trial.JAMA network open · 2025Trial
- Delivering the Thinking Healthy Programme as a universal group intervention integrated into routine antenatal care: a randomized-controlled pilot study.BMC psychiatry · 2023Trial
- Efficacy and cost-effectiveness of task-shared care for people with severe mental disorders in Ethiopia (TaSCS): a single-blind, randomised, controlled, phase 3 non-inferiority trial.The lancet. Psychiatry · 2022Trial
- Collaboration With People With Lived Experience of Mental Illness to Reduce Stigma and Improve Primary Care Services: A Pilot Cluster Randomized Clinical Trial.JAMA network open · 2021Trial
- Advancing forensic psychiatry in Rwanda: lessons learned and challenges.Global health action · 2026Article
- Prevalence and Associated Risk Factors of Psychiatric Comorbidities Among the Hospitalized Patients in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Enhancing the utility of exploratory 'factors associated with' studies in global mental health: the importance of context in Sub-Saharan Africa.International journal of mental health systems · 2026Article
- Adaptation and pilot implementation of the WHO guideline on digital intervention to strengthen mental health systems in Lagos state, Nigeria.Health research policy and systems · 2026Article
- Health Professionals' Perspectives on the Provision of Mental Health Services for People with Mental Health Problems and HIV: A Qualitative Study.Healthcare (Basel, Switzerland) · 2026Article
- Observational
- Improving mental health literacy of frontline community health workers in a rural district of Pakistan: mPareshan project.BJPsych open · 2026Article
- National implementation of a digital Parkinson's disease screening programme in Thailand: reach, adoption, and real-world performance of the CheckPD app.BMC public health · 2026Article
- Temporal relationship between physical activity, social anxiety, and internet addiction among adolescents: a cross-lagged analysis.Scientific reports · 2026Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
questionThere is a large worldwide gap between the service need and provision for mental, neurological and substance use disorders. WHO's Mental Health Gap Action Programme (mhGAP) intervention guide (IG), provides evidence-based guidance and tools for assessment and integrated management of priority disorders. Our 2017 systematic review identified 33 peer-reviewed studies describing mhGAP-IG implementation in low-income and middle-income countries. STUDY SELECTION AND ANALYSIS: We searched MEDLINE, Embase, PsycINFO, Web of Knowledge, Scopus, CINAHL, LILACS, ScieELO, Cochrane, PubMed databases, 3ie, Google Scholar and citations of our review, on 24 November 2020. We sought evidence, experience and evaluations of the mhGAP-IG, app or mhGAP Humanitarian IG, from any country, in any language. We extracted data from included papers, but heterogeneity prevented meta-analysis.
findingsOf 2621 results, 162 new papers reported applications of the mhGAP-IG. They described mhGAP training courses (59 references), clinical applications (n=49), research uses (n=27), contextual adaptations (n=13), economic studies (n=7) and other educational applications (n=7). Most were conducted in the African region (40%) and South-East Asia (25%). Studies demonstrated improved knowledge, attitudes and confidence post-training and improved symptoms and engagement with care, post-implementation. Research studies compared mhGAP-IG-enhanced usual care with task-shared psychological interventions and adaptation studies optimised mhGAP-IG implementation for different contexts. Economic studies calculated human resource requirements of scaling up mhGAP-IG implementation and other educational studies explored its potential for repurposing.
conclusionsThe diverse, expanding global mhGAP-IG literature demonstrates substantial impact on training, patient care, research and practice. Priorities for future research should be less-studied regions, severe mental illness and contextual adaptation of brief psychological interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.