Evidence map›Paper›PMID 33903104›Full record

ArticleAntimicrobial agents and chemotherapy2021

Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein 2.

Sangwoo Nam, Yun Ji Ga, Joo-Youn Lee, Woo-Yeon Hwang, Eunhye Jung, Jin Soo Shin, Weiyi Chen, Gildon Choi, Bin Zhou, Jung-Yong Yeh and 1 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Sangwoo Nam *Medicinal Chemistry and Pharmacology, University of Science and Technology, Daejeon, Republic of Korea.
Yun Ji Ga *Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Republic of Korea.
Joo-Youn LeeTherapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Woo-Yeon HwangTherapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Eunhye JungTherapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Jin Soo ShinTherapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Weiyi ChenDepartment of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine, City University of Hong Kong, Hong Kong SAR, China.
Gildon ChoiMedicinal Chemistry and Pharmacology, University of Science and Technology, Daejeon, Republic of Korea.
Bin ZhouMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Jung-Yong YehDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Republic of Korea.
Yun Young GoDepartment of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine, City University of Hong Kong, Hong Kong SAR, China.
Korea Research Institute of Chemical Technology · KRCity University of Hong Kong · HKIncheon National University · KRKorea University of Science and Technology · KRKyung Hee University · KRNanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes a debilitating febrile illness characterized by persistent muscle and joint pain. The widespread distribution of transmission-competent vectors,

Indexed as

Chikungunya FeverChikungunya virusAnimalsMacrolidesMosquito VectorsViral Nonstructural ProteinsVirus ReplicationMacrolidesmonordenViral Nonstructural ProteinsantiviralChikungunya virusHsp90Hsp90 inhibitornsP2radicicol

Identifiers

PMID33903104
PMCPMC8373223
OpenAlexW3157358099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.