Evidence map›Paper›PMID 33902815›Full record

ReviewJournal of magnetic resonance (San Diego, Calif. : 1997)2021

Deuterium metabolic imaging - Back to the future.

Henk M De Feyter, Robin A de Graaf

Abstract readReview
In one paragraph

Review in Journal of magnetic resonance (San Diego, Calif. : 1997), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  8. Review
  9. Article
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  12. Article
  13. Article
  14. Assessment of TMagma (New York, N.Y.) · 2026
    Article
  15. Article
  16. Article
  17. Combining DMI and [European radiology experimental · 2026
    Article
  18. A Stable Isotope Tracing Primer for the Mass Spectrometrist.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026
    Review
  19. Review
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Henk M De FeyterDepartments of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address: henk.defeyter@yale.edu.
Robin A de GraafDepartments of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address: robin.degraaf@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Deuterium metabolic imaging (DMI) of neurological diseaseR01EB025840 · NIBIB · YALE UNIVERSITY · PI ROBIN A DE GRAAF, Henk De Feyter · 2019 to 2026
$4.2M
NCATS NIH HHS UL1 TR001863NIBIB NIH HHS R01 EB025840
6 · The paper itself

Abstract

Deuterium metabolic spectroscopy (DMS) and imaging (DMI) have recently been described as simple and robust MR-based methods to map metabolism with high temporal and/or spatial resolution. The metabolic fate of a wide range of suitable deuterated substrates, including glucose and acetate, can be monitored with deuterium MR methods in which the favorable MR characteristics of deuterium prevent many of the complications that hamper other techniques. The short T

Indexed as

AcetatesDeuteriumGlucoseMagnetic Resonance SpectroscopyWaterAcetatesDeuteriumGlucoseWaterDeuteriumGlucoseLabel lossMetabolic imagingRelaxation

Identifiers

PMID33902815
PMCPMC8083995

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.