ArticleeLife2021
An agnostic study of associations between ABO and RhD blood group and phenome-wide disease risk.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Comparison of ABO Blood Group, Rh Factor, and Genotype Frequency Among University Students in Liberia and Pakistan: A Cross-Sectional Study.Health science reports · 2026Article
- Pediatric ABO blood groups and disease distribution: a retrospective analysis.Translational pediatrics · 2026Article
- The relationship between ABO blood types and clopidogrel-related low on-treatment platelet reactivity in patients with coronary artery diseases and type 2 diabetes mellitus: a secondary analysis of a prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- An agnostic study of donor and component factors associated with transfusion-related changes in laboratory markers.Transfusion · 2025Article
- ABO/rhesus D blood systems and health indices: a preliminary study to find an association among healthy dwellers of Anuradhapura, Sri Lanka.BMC research notes · 2025Article
- ABO and RhD blood groups as contributors to dyslipidaemia - a cross-sectional study.Lipids in health and disease · 2025Article
- Cancer incidence following non-neoplastic medical conditions: a prospective population-based cohort study.Acta oncologica (Stockholm, Sweden) · 2024Article
- Blood groups and Rhesus status as potential predictors of outcomes in patients with cardiac resynchronisation therapy.Scientific reports · 2024Article
- Association of ABO and Rhesus blood groups with severe outcomes from non-SARS-CoV-2 respiratory infection: A prospective observational cohort study in Bristol, UK 2020-2022.British journal of haematology · 2024Observational
- ABO Blood Groups, RhD Factor and Their Association with Subclinical Atherosclerosis Assessed by Carotid Ultrasonography.Journal of clinical medicine · 2024Article
- More evidence for widespread antagonistic pleiotropy in polymorphic disease alleles.Frontiers in genetics · 2024Review
- Blood group O is associated with ARDS development but exhibits lower mortality in the intensive care unit - A retrospective multicentre study.European clinical respiratory journal · 2024Article
- Evaluation of Clinical Manifestations of Hemorrhoidal Disease, Carried Out Surgeries and Prolapsed Anorectal Tissues: Associations with ABO Blood Groups of Patients.Journal of clinical medicine · 2023Article
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- Erythroprotective Potential of Phycobiliproteins Extracted fromMetabolites · 2023Article
- ABO, secretor, and Lewis carbohydrate histo-blood groups are associated with autoimmune neutropenia of early childhood in Danish patients.Transfusion · 2022Article
- The Clinical Utility of ABO and RHD Systems as Potential Indicators of Health Status, a Preliminary Study in Greek Population.Clinics and practice · 2022Article
- ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29 512 patients.BMC anesthesiology · 2022Observational
- Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus.Genes and immunity · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: There are multiple known associations between the ABO and RhD blood groups and disease. No systematic population-based studies elucidating associations between a large number of disease categories and blood group have been conducted. Methods: Using SCANDAT3-S, a comprehensive nationwide blood donation-transfusion database, we modeled outcomes for 1217 disease categories including 70 million person-years of follow-up, accruing from 5.1 million individuals. Results: We discovered 49 and 1 associations between a disease and ABO and RhD blood groups, respectively, after adjustment for multiple testing. We identified new associations such as a decreased risk of kidney stones and blood group B as compared to blood group O. We also expanded previous knowledge on other associations such as pregnancy-induced hypertension and blood groups A and AB as compared to blood group O and RhD positive as compared to negative. Conclusions: Our findings generate strong further support for previously known associations, but also indicate new interesting relations. Funding: Swedish Research Council.
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