Evidence map›Paper›PMID 33902513›Full record

Observational studyBMC pulmonary medicine2021

Clinical, radiological and functional outcomes in patients with SARS-CoV-2 pneumonia: a prospective observational study.

Pietro Gianella, Elia Rigamonti, Marco Marando, Adriana Tamburello, Lorenzo Grazioli Gauthier, Gianluca Argentieri, Carla Puligheddu, Alberto Pagnamenta, Marco Pons, Tanja Fusi-Schmidhauser

Erratum issuedOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Observational
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pietro GianellaDepartment of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Elia Rigamonti *Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Marco Marando *Department of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland. marco.marando@eoc.ch.
Adriana TamburelloDepartment of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Lorenzo Grazioli GauthierDepartment of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Gianluca ArgentieriIIMSI - Radiology Department, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Carla PulighedduIIMSI - Radiology Department, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Alberto PagnamentaDepartment of Intensive Care, Intensive Care Unit Ospedale Regionale Di Mendrisio, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Marco PonsDepartment of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Tanja Fusi-SchmidhauserDepartment of Internal Medicine, Ospedale Regionale Di Lugano, Ente Ospedaliero Cantonale, Via Tesserete 46, 6900, Lugano, Switzerland.
Ente Ospedaliero Cantonale · CHOspedale regionale di Lugano · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAll over the world, SARS-CoV-2 pneumonia is causing a significant short-term morbidity and mortality, but the medium-term impact on lung function and quality of life of affected patients are still unknown.

methodsIn this prospective observational study, 39 patients with SARS-CoV-2 pneumonia were recruited from a single COVID-19 hospital in Southern Switzerland. At three months patients underwent radiological and functional follow-up through CT scan, lung function tests, and 6 min walking test. Furthermore, quality of life was assessed through self-reported questionnaires.

resultsAmong 39 patients with SARS-CoV-2 pneumonia, 32 (82% of all participants) presented abnormalities in CT scan and 25 (64.1%) had lung function tests impairment at three months. Moreover, 31 patients (79.5%) reported a perception of poor health due to respiratory symptoms and all 39 patients showed an overall decreased quality of life.

conclusionsMedium-term follow up at three months of patients diagnosed with SARS-CoV-2 pneumonia shows the persistence of abnormalities in CT scans, a significant functional impairment assessed by lung function tests and a decreased quality of life in affected patients. Further studies evaluating the long-term impact are warranted to guarantee an appropriate follow-up to patients recovering from SARS-CoV-2 pneumonia.

Indexed as

Quality of LifeAgedConvalescenceCOVID-19FemaleForced Expiratory VolumeHealth StatusHumansLength of StayLungMaleMiddle AgedProspective StudiesPulmonary Diffusing CapacityRecovery of FunctionRespiratory Function Tests3-Month outcomeChest CTCOVID-19Pulmonary function tests

Identifiers

PMID33902513
PMCPMC8072729
OpenAlexW3159143079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.