Evidence map›Paper›PMID 33902388›Full record

ArticleJournal of environmental science and health. Part C, Toxicology and carcinogenesis2021

Short-term metabolic disruptions in urine of mouse models following exposure to low doses of oxygen ion radiation.

Michael Girgis, Yaoxiang Li, Meth Jayatilake, Kirandeep Gill, Sirao Wang, Kepher Makambi, Vijayalakshmi Sridharan, Amrita K Cheema

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael GirgisDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Yaoxiang LiDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Meth JayatilakeDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.ORCID 0000-0002-5780-9391
Kirandeep GillDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Sirao WangDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Kepher MakambiDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University Medical Center, Washington, DC, USA.
Vijayalakshmi SridharanDivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Amrita K CheemaDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI STEPHEN W BYERS · 1990 to 2026
$71.5M
The Protein C Pathway in Mitigation of Radiation-Induced Endothelial and Vascular DysfunctionU01AI133561 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BOERMA, MARJAN, GRIFFIN, JOHN H · 2017 to 2021
$3.3M
NCI NIH HHS P30 CA051008NIAID NIH HHS U01 AI133561
6 · The paper itself

Abstract

Molecular alterations as a result of exposure to low doses of high linear energy transfer (LET) radiation can have deleterious short- and long-term consequences on crew members embarking on long distance space missions. Oxygen ions (

Indexed as

Cosmic RadiationOxygenRadiation, IonizingAnimalsLinear Energy TransferMaleMetabolomicsMiceMice, Inbred C57BLUrineOxygenCosmic radiationhigh-LET charged particle radiationmetabolic dysregulationoxygen ion radiationurinary metabolites

Identifiers

PMID33902388
PMCPMC9757021

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.