Evidence map›Paper›PMID 33902363›Full record

ArticleTechnology in cancer research & treatment

S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.

Haopeng Wang, Mengyuan Yin, Lei Ye, Peng Gao, Xiang Mao, Xuefeng Tian, Ziao Xu, Xingliang Dai, Hongwei Cheng

Open access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Haopeng WangDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Mengyuan YinDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Lei YeDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Peng GaoDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiang MaoDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID 0000-0002-1897-2751
Xuefeng TianDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Ziao XuDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xingliang DaiDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Hongwei ChengDepartment of Neurosurgery, the First Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID 0000-0001-8239-3941
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of glioma is significantly correlated with the pathological grades; however, the correlations between the prognostic biomarkers with pathological grades have not been elucidated. S100A11 is involved in a variety of malignant biological processes of tumor, whereas its biological and clinicopathological features on glioma remain unclear. In this study, the S100A11 expression and clinical information were obtained from the public databases (TCGA, GEPIA2) to analyze its correlations with the pathological grade and the prognosis of glioma patients. We then verified the expression of S100A11 by immunohistochemistry staining. The effects of S100A11 on the proliferation of glioma cells were confirmed by cytological function assays (CCK-8, Flow cytometry, Clone formation assay)

Indexed as

Cell ProliferationGene Expression Regulation, NeoplasticAnimalsApoptosisBiomarkers, TumorBrain NeoplasmsCell CycleCell MovementGliomaHumansMiceMice, Inbred BALB CMice, NudePrognosisS100 ProteinsSurvival RateBiomarkers, TumorS100A11 protein, humanS100 ProteinsbiomarkersgliomaprognosisproliferationS100A11

Identifiers

PMID33902363
PMCPMC8085370
OpenAlexW3157289528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.