ArticleCirculation research2021
Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
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Who cites it
24 citing papers in PubMed, 33 citations in OpenAlex.
- PRDM16 as a Multifaceted Pharmacological Target in Kidney Diseases: From Epigenetic Mechanisms to Therapeutic Strategies.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Single-cell transcriptomics uncovers endothelial progenitor-like remodelling driving human coronary atherosclerosis progression.Nature cell biology · 2026Article
- Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake.Nature communications · 2026Article
- Coronary artery disease risk gene PRDM16 regulates smooth muscle homeostasis.Journal of molecular and cellular cardiology · 2026Article
- Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Immune Cell Type-Specific DNA Methylation Regions Associate With 24-Hour Blood Pressure Regulation in Black People.Journal of the American Heart Association · 2026Article
- The stroke risk gene Foxf2 maintains brain endothelial cell function via Tie2 signaling.Nature neuroscience · 2026Article
- Mechanistic Insight into PVAT Browning as a Protective Factor in Thoracic Aortic Aneurysm.Current atherosclerosis reports · 2026Review
- Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk.Nature genetics · 2026Article
- PRDM16 regulates smooth muscle cell identity and atherosclerotic plaque composition.Nature cardiovascular research · 2025Article
- Flipping the PRDM16 switch in 'multifunctional mesenchymes' may help to define atherosclerotic plaque.Nature cardiovascular research · 2025Article
- PRDM16, a new kid on the block in cardiovascular health and disease.Cardiovascular research · 2025Review
- Factors associated with blood pressure regulation in vascular smooth muscle cells.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.Life science alliance · 2024Article
- PBX/Knotted 1 homeobox-2 (PKNOX2) is a novel regulator of myocardial fibrosis.Signal transduction and targeted therapy · 2024Article
- Article
- PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm.JCI insight · 2023Article
- PRDM16 regulates arterial development and vascular integrity.Frontiers in physiology · 2023Article
- Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk.Nature genetics · 2022Article
- Developmental independence of median fins from the larval fin fold revises their evolutionary origin.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 2 countries.
Sander CrapsDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Jore Van WauweDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Sofie De MoudtPharmaceutical Sciences, Physiopharmacology, University of Antwerp, Antwerp, Belgium (S.D.M., D.D.M., A.J.A.L., P.F.).
Dorien De MunckPharmaceutical Sciences, Physiopharmacology, University of Antwerp, Antwerp, Belgium (S.D.M., D.D.M., A.J.A.L., P.F.).
Arthur J A LeloupPharmaceutical Sciences, Physiopharmacology, University of Antwerp, Antwerp, Belgium (S.D.M., D.D.M., A.J.A.L., P.F.).
Bram BoeckxLaboratory for Translational Genetics, Department of Human Genetics (B.B., D.L.), KU Leuven, Leuven, Belgium.
Tim VervlietLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine (T.V.), KU Leuven, Leuven, Belgium.
Wouter DheedeneDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Nathan CriemDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Carla GeeromsPrometheus, Division of Skeletal Tissue Engineering (C.G.), KU Leuven, Leuven, Belgium.
Elizabeth A V JonesDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
An ZwijsenDepartment of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Diether LambrechtsLaboratory for Translational Genetics, Department of Human Genetics (B.B., D.L.), KU Leuven, Leuven, Belgium.
Paul FransenPharmaceutical Sciences, Physiopharmacology, University of Antwerp, Antwerp, Belgium (S.D.M., D.D.M., A.J.A.L., P.F.).
Manu Beerens *Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
Aernout Luttun *Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology (S.C., J.V.W., W.D., N.C., E.A.V.J., A.Z., M.B., A.L.), KU Leuven, Leuven, Belgium.
KU Leuven · BEUniversity of Antwerp · BEVIB-KU Leuven Center for Cancer Biology · BEBrigham and Women's Hospital · USRega Institute for Medical Research · BE
Funding
No grant is acknowledged in the PubMed record.
Abstract
[Figure: see text].
Indexed as
Neovascularization, PhysiologicAnimalsAortaCalciumCalcium SignalingCells, CulturedCollateral CirculationDisease Models, AnimalDNA-Binding ProteinsEndothelial CellsEndothelium, VascularFemoral ArteryHindlimbIschemiaMaleMiceCalciumDNA-Binding ProteinsPrdm16 protein, mouseTranscription Factorsarteriesendotheliumhomeostasisischemiatranscription factorvasodilation
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What OpenQuestion holds
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.