Evidence map›Paper›PMID 33902007›Full record

ArticleAging2021

Targeting ATM to mitigate intervertebral disc degeneration.

Louise E Pitcher, Alec K Wong, Paul D Robbins

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louise E PitcherInstitute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Alec K WongInstitute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Paul D RobbinsInstitute on the Biology of Aging and Metabolism, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

Funding

Targeting Cellular Senescence to Extend HealthspanP01AG062413 · NIA · MAYO CLINIC ROCHESTER · PI Sundeep Khosla · 2019 to 2026
$28.7M
Validation and characterization of the identified variants associated with human longevity in mouse modelsU19AG056278 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JAN VIJG · 2017 to 2026
$24.5M
PROTEOMICSP01AG043376 · NIA · UNIVERSITY OF MINNESOTA · PI ROBBINS, PAUL D. · 2013 to 2019
$11.2M
Using the senolytic fisetin to suppress mortality in aged mice acutely exposed to murine beta-coronavirusR01AG063543 · NIA · UNIVERSITY OF MINNESOTA · PI NIEDERNHOFER, LAURA JANE · 2019 to 2023
$3.4M
The role of cellular senescence in intervertebral disc agingR01AG044376 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VO, NAM V · 2013 to 2017
$1.5M
NIA NIH HHS P01 AG043376NIA NIH HHS P01 AG062413NIA NIH HHS R01 AG044376NIA NIH HHS R01 AG063543NIA NIH HHS U19 AG056278
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Intervertebral DiscIntervertebral Disc DegenerationAtaxia Telangiectasia Mutated ProteinsCellular SenescenceHumansAtaxia Telangiectasia Mutated ProteinsATM protein, humanagingDNA damagesenescencesignal transduction

Identifiers

PMID33902007
PMCPMC8109090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.