Evidence map›Paper›PMID 33902006›Full record

ArticleAging2021

Effects of advanced glycation end products on neutrophil migration and aggregation in diabetic wounds.

Yutian Kang, Chongliang Zheng, Junna Ye, Fei Song, Xiqiao Wang, Yingkai Liu, Ming Tian, Jiaoyun Dong, Shuliang Lu

Open access · greenAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  15. Article
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  17. Article
  18. A Role for Advanced Glycation End Products in Molecular Ageing.International journal of molecular sciences · 2023
    Review
  19. Article
  20. [Research advances on the mechanism of refractory healing of diabetic foot ulcer].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yutian KangDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Chongliang ZhengDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Junna YeDepartment of Rheumatology and Immunology, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Fei SongDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Xiqiao WangDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Yingkai LiuDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Ming TianDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Jiaoyun DongDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Shuliang LuDepartment of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Shanghai Jiao Tong University · CNRuijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased accumulation of advanced glycation end products (AGEs) in diabetic skin is closely related to delayed wound healing. Studies have shown that the concentration of AGEs is elevated in the skin tissues and not subcutaneous tissues in refractory diabetic wounds, which suggests there may be a causal relationship between the two. In the present study,

Indexed as

AnimalsCateninsCell AggregationCell Line, TumorCell MovementDelta CateninDiabetes ComplicationsDiabetes Mellitus, ExperimentalGlycation End Products, AdvancedHumansMaleNeutrophilsRatsReceptors, VirusSkinStreptozocinCateninsDelta CateninGlycation End Products, Advancedpoliovirus receptorReceptors, VirusStreptozocinAGEsCTNND1diabetesneutrophil migrationwound repair

Identifiers

PMID33902006
PMCPMC8109105
OpenAlexW3159215788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.