Evidence map›Paper›PMID 33901808›Full record

ArticleRedox biology2021

A coupled enzyme assay for detection of selenium-binding protein 1 (SELENBP1) methanethiol oxidase (MTO) activity in mature enterocytes.

Thilo Magnus Philipp, Andreas Will, Hannes Richter, Patrick Rainer Winterhalter, Georg Pohnert, Holger Steinbrenner, Lars-Oliver Klotz

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  11. Altered Capacity for HAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thilo Magnus PhilippInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich Schiller University Jena, Jena, Germany.
Andreas WillInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich Schiller University Jena, Jena, Germany.
Hannes RichterInstitute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, Jena, Germany.
Patrick Rainer WinterhalterDepartment of Cardiac Surgery, Martin Luther University Halle-Wittenberg, Halle, Germany.
Georg PohnertInstitute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena, Jena, Germany.
Holger SteinbrennerInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich Schiller University Jena, Jena, Germany.
Lars-Oliver KlotzInstitute of Nutritional Sciences, Nutrigenomics Section, Friedrich Schiller University Jena, Jena, Germany. Electronic address: lars-oliver.klotz@uni-jena.de.
Friedrich Schiller University Jena · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methanethiol, a gas with the characteristic smell of rotten cabbage, is a product of microbial methionine degradation. In the human body, methanethiol originates primarily from bacteria residing in the lumen of the large intestine. Selenium-binding protein 1 (SELENBP1), a marker protein of mature enterocytes, has recently been identified as a methanethiol oxidase (MTO). It catalyzes the conversion of methanethiol to hydrogen sulfide (H

Indexed as

EnterocytesSelenium-Binding ProteinsCaco-2 CellsEnzyme AssaysHumansHydrogen PeroxideOxidoreductasesSulfhydryl CompoundsHydrogen PeroxidemethylmercaptanOxidoreductasesSELENBP1 protein, humanSelenium-Binding ProteinsSulfhydryl CompoundsCaco-2 cellsHydrogen peroxideHydrogen sulfideMethanethiol oxidaseSelenium-binding protein 1

Identifiers

PMID33901808
PMCPMC8099554
OpenAlexW3156649927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.