ArticleThe Journal of pediatrics2021
Racial and Ethnic Disparities in the Investigation and Treatment of Growth Hormone Deficiency.
Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Variability in the management of healthy short youth following GH stimulation testing.Endocrines · 2026Article
- Barriers to growth hormone access in pediatric patients at an academic medical center.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2026Article
- Correlates of youth involvement in decision making about growth hormone treatment.Families, systems & health : the journal of collaborative family healthcare · 2025Article
- Sex and racial/ethnic disparities in children presenting for short stature evaluation: in-depth analysis at a single center.Annals of pediatric endocrinology & metabolism · 2025Article
- Comparison of children with bioinactive growth hormone, small for gestational age, and idiopathic short stature.Frontiers in endocrinology · 2025Article
- Equity Concerns Across Pediatric Research Recruitment: An Analysis of Research Staff Interviews.Academic pediatrics · 2024Article
- Racial and ethnic inequities in the quality of paediatric care in the USA: a review of quantitative evidence.The Lancet. Child & adolescent health · 2024Review
- Patient and Parent Characteristics Related to Quality of Life and Self-Esteem in Healthy Youth Undergoing Provocative Growth Hormone Testing.The Journal of pediatrics · 2023Article
- Views on Short Stature of Female vs Male Endocrine Pediatric Patients Undergoing Provocative Growth Hormone Testing and Their Parents.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2023Article
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Assessment of childhood short stature: a GP guide.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023Article
- Perceptions of Youth and Parent Decision-Making Roles Regarding Recombinant Human Growth Hormone Treatment.Endocrines · 2022Article
- Identifying and addressing disparities in the evaluation and treatment of children with growth hormone deficiency.Frontiers in endocrinology · 2022Review
- Growth Hormone Stimulation Testing Patterns Contribute to Sex Differences in Pediatric Growth Hormone Treatment.Hormone research in paediatrics · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo determine if the racial/ethnic inequity in growth hormone (GH) use is due to differences in GH stimulation testing and/or prescribing patterns in children referred for endocrine evaluation of short stature. STUDY
designRetrospective chart review was performed including children aged 2-16 years, height z-score of ≤-1.5, and of non-Hispanic White (NHW), non-Hispanic Black (NHB), or Hispanic race/ethnicity, referred for endocrine growth evaluation between January 2012 and December 2019.
resultsThis study included 7425 children (5905 NHW, 800 NHB, and 720 Hispanic). GH stimulation testing was performed in 992, and 576 were prescribed GH. NHW children were 1.4 (95% CI, 1.04-1.8) times more likely than NHB children and 1.7 (95% CI, 1.2-2.2) times more likely than Hispanic children to undergo GH stimulation testing. GH-treated NHB children had (1) a lower median peak GH concentration when compared with NHW (P = .02) and Hispanic (P = .08) children (NHB 4.7 ng/mL [95% CI, 1.2-8.3 ng/mL] ng/mL, NHW 7.2 ng/mL [95% CI, 4.9-9.7 ng/mL], Hispanic 7.1 ng/mL [95% CI, 4.3-11.9 ng/mL]); (2) lower median height z-scores than NHW (P = .01) but not Hispanic children (P = .5); and (3) a greater height deficit from midparental height when compared with NHW (P = .01) and Hispanic (P = .002) children.
conclusionsRacial and ethnic disparities exist in the evaluation and treatment of children with disordered growth. This likely results from both overinvestigation of NHW children as well as underinvestigation and undertreatment of children from minority communities. The evaluation and treatment of children with short stature should be determined by clinical concern alone, but this is not current practice.
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