Evidence map›Paper›PMID 33901438›Full record

ArticleArchives of physical medicine and rehabilitation2021

Associations of Multiple Chronic Conditions With Physical Performance and Falls Among Older Adults With Back Pain: A Longitudinal, Population-based Study.

Sean D Rundell, Amol Karmarkar, Michael Nash, Kushang V Patel

Open access · greenAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Adolescent IQ and performance-based measures of physical function in old age: a 54-year longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
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  12. Fear of Falling: Exploring Associated Factors among Elderly Residents in the Rural Communities of Vietnam.International journal of environmental research and public health · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sean D RundellDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA; Department of Health Services, University of Washington, Seattle, WA. Electronic address: srundell@uw.edu.
Amol KarmarkarDepartment of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA; Sheltering Arms Institute, Richmond, VA.
Michael NashCenter for Biomedical Statistics, University of Washington, Seattle, WA.
Kushang V PatelDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
University of Washington · USVirginia Commonwealth University · US

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
Technique Development CoreP2CHD065702 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI OTTENBACHER, KENNETH J. · 2015 to 2019
$5.2M
Center for Rehabilitation Research Using Large DatasetsR24HD065702 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI OTTENBACHER, KENNETH J. · 2010 to 2014
$4.0M
Comparing Access and Effectiveness of Post-Acute Care Settings Among Medicare BeneficiariesK01HD086290 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI KARMARKAR, AMOL · 2016 to 2020
$636k
NIA NIH HHS U01 AG032947NICHD NIH HHS K01 HD086290NICHD NIH HHS P2C HD065702NICHD NIH HHS R24 HD065702
6 · The paper itself

Abstract

objectiveTo determine the association of chronic conditions measured at baseline with physical performance and falls over time among older adults with back pain. We examined both number and type (depression, anxiety, arthritis) of chronic conditions.

designRetrospective cohort study.

settingNational Health and Aging Trends Study.

participantsA total of 2438 community-dwelling Medicare beneficiaries aged ≥65 years with bothersome back pain (N=2438). The sample was mostly female (62%; 95% confidence interval [CI], 59%-64%) and aged 65-74 years (56%; 95% CI, 53%-58%).

interventionsNot applicable.

main outcome measuresShort Physical Performance Battery (SPPB) (range, 0-12, lower indicates worse function) and recurrent falls measured annually over 6 years.

resultsMultiple chronic conditions were highly prevalent (82%; 95% CI, 79%-84%) among those reporting back pain. Adjusted regressions using survey weights with Taylor series linearization method and containing interaction terms for comorbidity and time showed having 2-3 chronic conditions vs 0-1 was associated with lower SPPB scores, and differences grew over time (for example 0.61 points lower [95% CI, -0.88 to -0.34] and 1.22 points lower [95% CI, -1.76 to -0.67] in rounds 3 and 6, respectively). Having ≥4 chronic conditions was associated with lower SPPB scores at all time points vs 0-1 (point estimate range, -1.72 to -2.31). Arthritis alone; the combination of arthritis with depression; and the triad of arthritis, depression, and anxiety were associated with lower SPPB scores at all time points. Logistic regression models showed presence of 2-3 and ≥4 chronic conditions was associated with increased odds of recurrent falls in any given year (odds ratio, 1.91; 95% CI, 1.35-2.69 and odds ratio, 3.92; 95% CI, 2.81-5.46, respectively). Those with the triad of arthritis, depression, and anxiety had greater odds of recurrent falls vs none or 1 condition.

conclusionsAmong older adults with back pain, those with multiple chronic conditions, including co-occurrence of arthritis, depression, and anxiety, have greater risk for poor physical functioning and falls over time.

Indexed as

Accidental FallsMultiple Chronic ConditionsPhysical Functional PerformanceAgedAged, 80 and overBack PainChronic DiseaseCohort StudiesFemaleHumansLongitudinal StudiesMaleRetrospective StudiesSurveys and QuestionnairesUnited StatesAgingBack painFallsFunctional statusMultimorbidityRehabilitation

Identifiers

PMID33901438
PMCPMC8429055
OpenAlexW3157093845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.