ArticlePloS one2021
Modifiable and unmodifiable factors associated with slow flow following rotational atherectomy.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Comparison of the incidence of slow flow following rotational atherectomy to severely calcified coronary artery lesions between short single session and long single session strategies: the randomized ROTASOLO trial.Cardiovascular intervention and therapeutics · 2025Trial
- Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics: update 2026.Cardiovascular intervention and therapeutics · 2026Review
- Changes in incidence of rotablation-induced coronary perforation by modifying practice over time: experiences at a high-volume center.Frontiers in cardiovascular medicine · 2026Article
- Management of Calcified Coronary Lesions-A Review of Plaque Modification Methods.Journal of clinical medicine · 2025Review
- Prognostic significance of angiography-derived index of microcirculatory resistance assessment after rotational atherectomy in patients with severely calcified lesions.Heart and vessels · 2025Article
- Predictive value of the CHA₂DS₂-VASc-HSF score for slow flow during rotational atherectomy in patients with severe coronary artery calcification.BMC cardiovascular disorders · 2025Article
- Percutaneous Revascularization of Thrombotic and Calcified Coronary Lesions.Journal of clinical medicine · 2025Review
- The application of rotational atherectomy in PCI for patients with complex coronary artery calcified lesions.American journal of translational research · 2025Article
- Halftime rotational atherectomy: a unique concept for diffuse long severely calcified lesions.Cardiovascular intervention and therapeutics · 2024Article
- Secondary rotational atherectomy is associated with reduced occurrence of prolonged ST-segment elevation following ablation.Internal and emergency medicine · 2023Article
- Comparison of Orbital Atherectomy and Rotational Atherectomy in Calcified Left Main Disease: Short-Term Outcomes.Journal of clinical medicine · 2023Article
- Clinical Outcomes and Unique Restenosis of Calcified Nodule in Heavily Calcified Coronary Artery.Journal of atherosclerosis and thrombosis · 2023Article
- Clinical expert consensus document on rotational atherectomy from the Japanese association of cardiovascular intervention and therapeutics: update 2023.Cardiovascular intervention and therapeutics · 2023Review
- Article
- Rota-Lithotripsy as a Novel Bail-Out Strategy for Highly Calcified Coronary Lesions in Acute Coronary Syndrome.Biomedicines · 2022Article
- Intravascular ultrasound-factors associated with slow flow following rotational atherectomy in heavily calcified coronary artery.Scientific reports · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough several groups reported the risk factors for slow flow during rotational atherectomy (RA), they did not clearly distinguish modifiable factors, such as burr-to-artery ratio from unmodifiable ones, such as lesion length. The aim of this retrospective study was to investigate the modifiable and unmodifiable factors that were associated with slow flow.
methodsWe included 513 lesions treated with RA, which were classified into a slow flow group (n = 97) and a non-slow flow group (n = 416) according to the presence or absence of slow flow just after RA. The multivariate logistic regression analysis was performed to find factors associated with slow flow.
resultsSlow flow was inversely associated with reference diameter [Odds ratio (OR) 0.351, 95% confidence interval (CI) 0.205-0.600, p<0.001], primary RA strategy (OR 0.224, 95% CI 0.097-0.513, p<0.001), short single run (≤15 seconds) (OR 0.458, 95% CI 0.271-0.776, p = 0.004), and systolic blood pressure (BP) ≥ 140 mmHg (OR 0.501, 95% CI 0.297-0.843, p = 0.009). Lesion length (every 5 mm increase: OR 1.193, 95% CI 1.093-1.301, p<0.001), angulation (OR 2.054, 95% CI 1.171-3.601, p = 0.012), halfway RA (OR 2.027, 95% CI 1.130-3.635, p = 0.018), initial burr-to-artery ratio (OR 1.451, 95% CI 1.212-1.737, p<0.001), and use of beta blockers (OR 1.894, 95% CI 1.004-3.573, p = 0.049) were significantly associated with slow flow.
conclusionsSlow flow was positively associated with several unmodifiable factors including lesion length and angulation, and inversely associated with reference diameter. In addition, slow flow was positively associated with several modifiable factors including initial burr-to-artery ratio and use of beta blockers, and inversely associated with primary RA strategy, short single run, and systolic blood pressure just before RA. Application of this information could help to improve RA procedures.
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