Evidence map›Paper›PMID 33901229›Full record

ArticlePloS one2021

Characteristics of adolescents aged 15-19 years living with vertically and horizontally acquired HIV in Nampula, Mozambique.

Chloe A Teasdale, Kirsty Brittain, Allison Zerbe, Claude Ann Mellins, Joana Falcao, Aleny Couto, Eduarda Pimentel De Gusmao, Mirriah Vitale, Bill Kapogiannis, Teresa Beatriz Simione and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Chloe A TeasdaleDepartment of Epidemiology and Biostatistics, CUNY Graduate School of Public Health & Health Policy, New York, New York, United States of America.ORCID 0000-0001-9165-8972
Kirsty BrittainDivision of Epidemiology & Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Allison ZerbeICAP at Columbia University, Mailman School of Public Health, New York, New York, United States of America.
Claude Ann MellinsDepartment of Psychiatry, HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University Irving Medical Center, New York, New York, United States of America.
Joana FalcaoICAP at Columbia University, Mailman School of Public Health, New York, New York, United States of America.
Aleny CoutoNational STI, HIV/AIDS Control Program, Maputo, Mozambique.
Eduarda Pimentel De GusmaoICAP at Columbia University, Mailman School of Public Health, New York, New York, United States of America.
Mirriah VitaleICAP at Columbia University, Mailman School of Public Health, New York, New York, United States of America.
Bill KapogiannisEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, United States of America.
Teresa Beatriz SimioneNational STI, HIV/AIDS Control Program, Maputo, Mozambique.
Landon MyerDivision of Epidemiology & Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa.
Joanne MantellDepartment of Psychiatry, HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University Irving Medical Center, New York, New York, United States of America.ORCID 0000-0002-0748-5974
Christopher DesmondCentre for Rural Health, University of KwaZulu Natal, Durban, South Africa.
Elaine J AbramsICAP at Columbia University, Mailman School of Public Health, New York, New York, United States of America.
ICAP Global HealthNational Directorate of Geology · MZNew York Psychoanalytic Society and Institute · USUniversity of Cape Town · ZAEunice Kennedy Shriver National Institute of Child Health and Human Development · USThe Graduate Center, CUNY · USUniversity of KwaZulu-Natal · ZA

Funding

CombinADO: a combination intervention strategy to improve health outcomes for adolescents living with HIVUG3HD096926 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ABRAMS, ELAINE JANINE · 2018 to 2019
$2.2M
NICHD NIH HHS UG3 HD096926
6 · The paper itself

Abstract

backgroundAdolescents living with HIV (ALHIV) 15-19 years of age are a growing proportion of all people living with HIV globally and the population includes adolescents with vertically acquired HIV (AVH) and behaviorally acquired HIV (ABH).

methodsWe conducted a survey to measure sociodemographic characteristics, educational status, health history, and antiretroviral therapy (ART) adherence among a convenience sample of ALHIV at three government health facilities in 2019 in Nampula, Mozambique. ALHIV 15-19 years on ART, including females attending antenatal care, were eligible. Routine HIV care data were extracted from medical charts. Classification of ALHIV by mode of transmission was based on medical charts and survey data. ALHIV who initiated ART <15 years or reported no sex were considered AVH; all others ABH. Frequencies were compared by sex, and within sex, by mode of transmission (AVH vs. ABH) using Chi-square, Fishers exact tests and Wilcoxon rank-sum tests.

resultsAmong 208 ALHIV, 143 (69%) were female and median age was 18 years [interquartile range (IQR) 16-19]. Just over half of ALHIV (53%) were in or had completed secondary or higher levels of education; the most common reason for not being in school reported by 36% of females was pregnancy or having a child. Of all ALHIV, 122 (59%) had VL data, 62% of whom were <1000 copies/mL. Almost half (46%) of ALHIV reported missing ARVs ≥ 1 day in the past month (62% of males vs. 39% of females; p = 0.003). Just over half (58%) of ALHIV in relationships had disclosed their HIV status: 13% of males vs. 69% of females (p<0.001). Among sexually active males, 61% reported using a condom at last sex compared to 26% of females (p<0.001). Among female ALHIV, 50 (35%) were AVH and 93 (65%) were ABH, 67% of whom were not in school compared to 16% of ABH, (p<0.001). DISCUSSION: Data from our study underscore the high level of deprivation among ALHIV enrolled in HIV care in Mozambique, as well as important disparities by sex and mode of transmission. These data can inform the development of effective interventions for this complex and important population.

Indexed as

AdolescentAnti-Retroviral AgentsCondomsDrug MonitoringEducational StatusFemaleHIV-1HIV InfectionsHumansMaleMedical History TakingMozambiqueSexual BehaviorYoung AdultAnti-Retroviral Agents

Identifiers

PMID33901229
PMCPMC8075210
OpenAlexW3158478197

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.