ArticleInternational journal of spine surgery2021
Combined Depression and Anxiety Influence Patient-Reported Outcomes after Lumbar Fusion.
Article in International journal of spine surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Implications of Preoperative Depression for Lumbar Spine Surgery Outcomes: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Surgical decompression timing for patients with foot drop from lumbar degenerative diseases: a meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Pooled it
- Association of glucagon-like peptide-1 receptor agonist use with patient-reported outcomes after lumbar decompression or fusion.North American Spine Society journal · 2026Article
- Impact of Depression and Anxiety on Outcomes Following Muscle-Preserving Transforaminal Lumbar Interbody and Fusion.Cureus · 2026Article
- Trajectory and influencing factors of changes in anxiety and depression in elderly patients after lumbar interbody fusion.World journal of psychiatry · 2026Article
- Clinical Setting Does Not Impact Baseline Patient Reported Outcomes Measures in Patients Undergoing Anterior Cervical Diskectomy and Fusion: A Prospective Study.Journal of clinical medicine · 2025Article
- Surgeon interpretation of patient-reported outcome measures in upper extremity osteoarthritis.PloS one · 2025Article
- The association of pre-existing mental health conditions and patient outcomes after lower extremity orthopaedic trauma: a scoping review.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Vitamin D deficiency during the perioperative period increases the rate of hardware failure and the need for revision fusion in adult patients undergoing single-level lumbar spine instrumentation surgery.North American Spine Society journal · 2023Article
- Does Baseline Mental Health Influence Outcomes among Workers' Compensation Claimants Undergoing Minimally Invasive Transforaminal Lumbar Interbody Fusion?Asian spine journal · 2023Article
Corrections and comments
- Erratum issuedCorrections.2023
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrently, no studies have assessed what effect the presence of both anxiety and depression may have on patient-reported outcome measurements (PROMs) compared to patients with a single or no mental health diagnosis.
methodsPatients undergoing 1- to 3-level lumbar fusion at a single academic hospital were retrospectively queried. Anyone with depression and/or anxiety was identified using an existing clinical diagnosis in the medical chart. Patients were separated into 3 groups: no depression or anxiety (NDA), depression or anxiety alone (DOA), and combined depression and anxiety (DAA). Absolute PROMs, recovery ratios, and the percentage of patients achieving minimal clinically important difference (% MCID) between groups were compared using univariate and multivariate analysis.
resultsOf the 391 patients included in the cohort, 323 (82.6%) were in the NDA group, 37 (9.5%) in the DOA group, and 31 (7.9%) in the DAA group. Patients in the DAA group had significantly worse outcome scores before and after surgery with respect to Short Form-12 mental component score (MCS-12) and Oswestry Disability Index (ODI) scores (
conclusionsPatients with combined anxiety and depression fared worse with respect to disability before and after surgery compared to patients with a single diagnosis or no mental health diagnosis; however, there were no significant differences in recovery ratio or % MCID. LEVEL OF EVIDENCE: 3. CLINICAL RELEVANCE: Combined anxiety and depression may predict less improvement in MCS-12 and ODI after lumbar arthrodesis compared with single or no mental health diagnosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.