Evidence map›Paper›PMID 33900867›Full record

ArticleThe Journal of international medical research2021

Prognostic value of peripheral blood inflammatory cell subsets in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Xiuxin Gao, Yixiang Liu, Yanan Tian, Chongyou Rao, Fei Shi, Haiwei Bu, Jingyi Liu, Ying Zhang, Weichao Shan, Zhenjiang Ding and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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  14. The Prognostic Value of Hematologic Inflammatory Markers in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xiuxin GaoDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Yixiang LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Yanan TianDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Chongyou RaoDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Fei ShiDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Haiwei BuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Jingyi LiuDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Ying ZhangDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Weichao ShanDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Zhenjiang DingDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.
Lixian SunDepartment of Cardiology, The Affiliated Hospital of Chengde Medical University, Chengde, HeBei, China.ORCID https://orcid.org/0000-0001-9814-0965
Chengde Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the predictive value of inflammatory cells in peripheral blood on the prognosis of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI).

methodsPatients (n=1558) were consecutively enrolled and the median follow-up was 1142 days. Patients were divided into the major adverse cardiac events (MACE) 1 group (n=63) (all-cause mortality [n=58] and rehospitalization for severe heart failure [n=5], no MACE1 group (n=1495), MACE2 group (n=38) (cardiac mortality [n=33] and rehospitalization for severe heart failure [n=5]), and no MACE2 group (n=1520). The neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) were analyzed.

resultsThe NLR, MLR, and PLR were higher in the MACE groups than in the no MACE groups. Different subsets of inflammatory cells had similar diagnostic values for MACE. Kaplan-Meier curves showed that the survival time gradually decreased with an increase in the degree of risk as determined by the NLR, MLR, and PLR. The risk of MACE was highest in the extremely high-risk group.

conclusionPeripheral blood inflammatory cell subsets can predict MACE in patients with ACS undergoing PCI. These cell subsets could be important laboratory markers for the prognosis and clinical treatment of these patients.

Indexed as

Acute Coronary SyndromePercutaneous Coronary InterventionHumansLymphocytesNeutrophilsPrognosisRetrospective StudiesAcute coronary syndromemajor adverse cardiac eventmonocyteneutrophil-to-lymphocyte ratioplateletprognosis

Identifiers

PMID33900867
PMCPMC8755652
OpenAlexW3159936314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.