ArticleThe Journal of organic chemistry2021
Desymmetrization Approach to the Synthesis of Optically Active P-Stereogenic Phosphin-2-en-4-ones.
Article in The Journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Design, synthesis and bioactivity evaluation of phosphinanes as potential anticancer agents.Scientific reports · 2025Article
- A Straightforward Approach Towards Phosphadecalones by Microwave-Assisted Diels-Alder Reaction.Molecules (Basel, Switzerland) · 2025Article
- Novel BicyclicMolecules (Basel, Switzerland) · 2024Article
- Resolution of P-Sterogenic 1-Phenylphosphin-2-en-4-one 1-Oxide into Two Enantiomers by (Molecules (Basel, Switzerland) · 2021Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two synthetic protocols for the conversion of 1-phenylphosphinan-4-ones to novel P-stereogenic 1-phenylphosphin-2-en-4-ones by enantioselective deprotonation followed by oxidation and by asymmetric organocatalytic halogenation accompanied by elimination have been developed. These two-step one-pot transformations provide convenient access to optically active 1-phenylphosphin-2-en-4-one 1-sulfide and 1-phenylphosphin-2-en-4-one 1-oxide of 96 and 55% enantiomeric purities, respectively.
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Registered trials
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