Evidence map›Paper›PMID 33900678›Full record

ArticleTurkish journal of pharmaceutical sciences2021

Comparative Proteomic Analysis of

Engin Koçak, Ceren Özkul

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Peptide Sequence of Pili Subunit Protein 49.8 kDaTurkish journal of pharmaceutical sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Engin KoçakHacettepe University Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, TurkeyORCID 0000-0002-1076-1300
Ceren ÖzkulHacettepe University Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Ankara, TurkeyORCID 0000-0002-0921-5863
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: In the present study, proteomics was utilized to evaluate changes in Materials and Methods: Proteomics analysis of Results: In total, 649 common proteins were identified in the untreated and ofloxacin-treated groups, while 98 proteins were significantly different in the ofloxacin-treated group. Functional classification and pathway analysis showed that ofloxacin has a systematic effect over ribosomal processes, energy pathways (tricarboxylic acid cycle and glycolysis), membrane proteins, microbial targets, and biofilm formation. Conclusion: The results showed that ofloxacin affected many cellular processes and pathways. In addition, proteomic analysis revealed that

Indexed as

antibiotic resistanceE. coliLC/MSofloxacinProteomics

Identifiers

PMID33900678
PMCPMC8100786
OpenAlexW3010124218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.