Evidence map›Paper›PMID 33900108›Full record

ArticlePhysiological genomics2021

Genomic and epigenomic active vitamin D responses in human colonic organoids.

Jinchao Li, David Witonsky, Emily Sprague, Dereck Alleyne, Maggie C Bielski, Kristi M Lawrence, Sonia S Kupfer

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinchao LiSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
David WitonskySection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Emily SpragueSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Dereck AlleyneSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Maggie C BielskiSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Kristi M LawrenceSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
Sonia S KupferSection of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago, Chicago, Illinois.
University of Chicago · US

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 1990 to 2025
$29.8M
FITting noninvasive testing into Lynch syndrome colorectal cancer surveillance: a multicenter, prospective trialR01CA287257 · NCI · UNIVERSITY OF CHICAGO · PI Fay Kastrinos, Sonia Kupfer · 2024 to 2026
$3.4M
University of Arizona's Initiative for Maximizing Student Development (IMSD)T32GM139779 · NIGMS · UNIVERSITY OF ARIZONA · PI FRANS E TAX · 2022 to 2026
$2.9M
Graduate Training in Biochemistry and Molecular BiologyT32GM136536 · NIGMS · UNIVERSITY OF ARIZONA · PI Andrew Paul Capaldi, FRANS E TAX · 2020 to 2026
$2.4M
Colonic responses to vitamin D and aspirin in African- and European-AmericansR01CA220329 · NCI · UNIVERSITY OF CHICAGO · PI KUPFER, SONIA · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA220329NCI NIH HHS R01 CA287257NIDDK NIH HHS P30 DK042086NIGMS NIH HHS T32 GM136536NIGMS NIH HHS T32 GM139779
6 · The paper itself

Abstract

Active vitamin D, 1α,25(OH)

Indexed as

CalcitriolChromatinChromatin Immunoprecipitation SequencingColonEpigenomicsGenomicsHumansMaleMiddle AgedOrganoidsRNA-SeqTime FactorsTranscriptional ActivationTranscriptomeVitamin D3 24-HydroxylaseVitaminsCalcitriolChromatinVitamin D3 24-HydroxylaseVitaminschromatin accessibilityorganoidstranscriptional responsesvitamin D

Identifiers

PMID33900108
PMCPMC8285575
OpenAlexW3157065260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.