Evidence map›Paper›PMID 33899625›Full record

ArticleClinical and experimental hypertension (New York, N.Y. : 1993)2021

Genetic variants of GRK4 influence circadian rhythm of blood pressure and response to candesartan in hypertensive patients.

Nian Cao, Hui Tang, Miao Tian, Xue Gong, Zaicheng Xu, Binqing Zhou, Cong Lan, Caiyu Chen, Shuang Qu, Shuo Zheng and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental hypertension (New York, N.Y. : 1993), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Nian CaoDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Hui TangDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Miao TianDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Xue GongDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Zaicheng XuDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Binqing ZhouDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Cong LanDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Caiyu ChenDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Shuang QuDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Shuo ZhengDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Hongmei RenDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Chao FanDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Pedro A JoseDepartment of Medicine and Pharmacology-Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Chunyu ZengDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Tianyang XiaDepartment of Cardiology, Daping Hospital, Third Military Medical University, Chongqing, P.R. China.
Daping Hospital · CNArmy Medical University · CNGeorge Washington University · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI JOSE, PEDRO A. · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
GRK4 & Development of Salt SensitivityR01HL092196 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES, JOSE, PEDRO A. · 2008 to 2017
$3.6M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL092196NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK119652
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood Pressure Monitoring, AmbulatoryCircadian RhythmHypertensionAntihypertensive AgentsBenzimidazolesBiphenyl CompoundsBlood PressureGenetic VariationG-Protein-Coupled Receptor Kinase 4HumansTetrazolesAntihypertensive AgentsBenzimidazolesBiphenyl CompoundscandesartanG-Protein-Coupled Receptor Kinase 4GRK4 protein, humanTetrazolescandesartancircadian rhythmEssential hypertensionGRK4

Identifiers

PMID33899625
PMCPMC8565180
OpenAlexW3159246126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.