Evidence map›Paper›PMID 33899541›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

Effects of hydrogen as adjuvant treatment for unstable angina.

Yanhong Si, Hua Tian, Bingqing Dong, Ying Zhang, Yuanyuan Wen, Xiubin Jia, Ying Li, Aihua Zhang, Shucun Qin

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  2. Review
  3. HMolecular and cellular biochemistry · 2026
    Review
  4. Review
  5. Expression Analysis ofInternational journal of molecular and cellular medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yanhong SiBasic Medical College, Shandong First Medical University, Shandong 271000, China.ORCID 0000-0002-2318-8080
Hua TianKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Bingqing DongThe Second Affiliated Hospital of Shandong First Medical University, Shandong 271000, China.
Ying ZhangKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Yuanyuan WenKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Xiubin JiaKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Ying LiKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Aihua ZhangNursing College, Shandong First Medical University, Shandong 271000, China.
Shucun QinKey Laboratory of Atherosclerosis in Universities of Shandong and Institute of Atherosclerosis, Shandong First Medical University, Shandong 271000, China.
Shandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and inflammation are closely related to atherosclerotic cardiovascular disease. It is established that hydrogen has significant protective effects on many diseases as a potential antioxidative and anti-inflammatory agent. The purpose of this study is to evaluate the effect of hydrogen on unstable angina

Indexed as

Angina, UnstableAnti-Inflammatory AgentsAntioxidantsAtherosclerosisCells, CulturedHumansHuman Umbilical Vein Endothelial CellsHydrogenInflammationLipoproteins, LDLOxidative StressSignal TransductionAnti-Inflammatory AgentsAntioxidantsHydrogenLipoproteins, LDLoxidized low density lipoproteinatherosclerosis: Hydrogeninflammationlectin-like oxidized low-density lipoprotein receptor-1NF-κB p65oxidative stressunstable angina

Identifiers

PMID33899541
PMCPMC8474983
OpenAlexW3159223764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.