Evidence map›Paper›PMID 33899511›Full record

ArticleStem cells and development2021

Murine Model of Cardiac Defects Observed in Adams-Oliver Syndrome Driven by

Prashan De Zoysa, Omar Toubat, Drayton Harvey, Jongkyu Choi, S Ram Kumar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells and development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Prashan De ZoysaDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-2788-7006
Omar ToubatDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California, USA.
Drayton HarveyDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California, USA.
Jongkyu ChoiDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California, USA.
S Ram KumarDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, California, USA.
University of Southern California · US

Funding

Training in Developmental Biology, Stem Cells and RegenerationT32HD060549 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Gage D Crump · 2011 to 2026
$2.5M
Role of delta-like ligand-4 signaling in cardiac outflow tract developmentK08HL121191 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SUBRAMANYAN, RAM KUMAR · 2016 to 2020
$843k
Malposed Semilunar Valves in Double Outlet Right Ventricle - A Pilot Genetic AnalysisR03HL154301 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SUBRAMANYAN, RAM KUMAR · 2020 to 2021
$165k
Prox1 and COUP-TFII interactions regulate lymphatic endothelial cell differentiationF30HL154324 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOUBAT, OMAR · 2020 to 2022
$115k
NHLBI NIH HHS F30 HL154324NHLBI NIH HHS K08 HL121191NHLBI NIH HHS R03 HL154301NICHD NIH HHS T32 HD060549
6 · The paper itself

Abstract

Heterozygous loss-of-function mutation in Delta-like ligand-4 (

Indexed as

HaploinsufficiencyLimb Deformities, CongenitalAnimalsDisease Models, AnimalEctodermal DysplasiaHumansLigandsMiceScalp DermatosesLigandscardiac developmentDelta-like ligand-4Dll4Notch signalingoutflow tractsecond heart fieldSHF

Identifiers

PMID33899511
PMCPMC8215425
OpenAlexW3157111759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.