ReviewAntioxidants & redox signaling2021
Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease.
Open access · greenAbstract readReview
In one paragraph
Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Therapeutic potential of nitric oxide and its donors in hemorrhagic and ischemic stroke: a systematic review.Medical gas research · 2026Pooled it
- Metabolic Reprogramming of Cancer Stem Cells: Targeting Lipid Flux and Mitochondrial Plasticity to Overcome Therapeutic Resistance.Cancer medicine · 2026Review
- Molecular Interplay of Brucellosis and Tuberculosis: Insights into Telomere Biology, Oxidative Stress, and Drug Resistance Mechanisms.Diseases (Basel, Switzerland) · 2026Review
- Metabolic Reprogramming of Microglia in Neuroinflammation and Depression.International journal of molecular sciences · 2026Review
- SC2-3, a Marine Nutrient Glycopeptide fromFoods (Basel, Switzerland) · 2026Article
- NO-cGMP Signaling in Endothelial Function of the Healthy and Inflamed Dental Pulp.International journal of molecular sciences · 2025Review
- The ketogenic diet in Parkinson's disease: a potential therapeutic strategy.Pharmacological reports : PR · 2025Review
- Role of Matricellular Proteins in Endothelial Cell Inflammation and Atherosclerosis.Antioxidants (Basel, Switzerland) · 2025Review
- Primary Cilia and Cardiovascular Risk Factors in Alzheimer's Disease.Brain sciences · 2025Review
- SKP2 ubiquitylation modifies IDH1 to regulate hepatoblastoma cell cycle and glucose metabolism.BMC cancer · 2025Article
- Antioxidants and Reactive Oxygen Species: Shaping Human Health and Disease Outcomes.International journal of molecular sciences · 2025Review
- Article
- Review
- Antioxidant interventions reduced cytokine-induced pyroptosis of peripheral MAIT cells in patients with HBV-related cirrhosis.Hepatology communications · 2025Article
- Short-Term Inhibition of NOX2 Prevents the Development of Aβ-Induced Pathology in Mice.Antioxidants (Basel, Switzerland) · 2025Article
- Redox Imbalance in Inflammation: The Interplay of Oxidative and Reductive Stress.Antioxidants (Basel, Switzerland) · 2025Review
- Differential aortic aneurysm formation provoked by chemogenetic oxidative stress.The Journal of clinical investigation · 2025Article
- Harnessing Gasotransmitters to Combat Age-Related Oxidative Stress in Smooth Muscle and Endothelial Cells.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Transcription Factor Blimp-1: A Central Regulator of Oxidative Stress and Metabolic Reprogramming in Chronic Inflammatory Diseases.Antioxidants (Basel, Switzerland) · 2025Review
- Recent progress in small-molecule fluorescent probes for the detection of superoxide anion, nitric oxide, and peroxynitrite anion in biological systems.Chemical science · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Masuko Ushio-FukaiVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.ORCID 0000-0001-7048-2381
Dipankar AshVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Sheela NagarkotiVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Eric J Belin de ChantemèleVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
David J R FultonVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Tohru FukaiVascular Biology Center, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.ORCID 0000-0001-9864-571X
Augusta University · US
Funding
Redox Regulation of Cu Importer CTR1 in AngiogenesisR01HL147550 · NHLBI · AUGUSTA UNIVERSITY · PI FUKAI, TOHRU, USHIO-FUKAI, MASUKO · 2020 to 2023
$3.3MCopper transport protein and inflammatory angiogenesisR01HL116976 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FUKAI, TOHRU, USHIO-FUKAI, MASUKO · 2013 to 2016
$2.9MCircadian origins of vascular disease in obesityR01HL147159 · NHLBI · AUGUSTA UNIVERSITY · PI FULTON, DAVID J, STEPP, DAVID W · 2019 to 2022
$2.7MCu Transporting ATPase and Diabetic Vascular ComplicationsR01HL133613 · NHLBI · AUGUSTA UNIVERSITY · PI FUKAI, TOHRU, USHIO-FUKAI, MASUKO · 2017 to 2020
$2.7MMechanism of cardiovascular disease in premenopausal womenR01HL155265 · NHLBI · AUGUSTA UNIVERSITY · PI BELIN DE CHANTEMELE, ERIC J · 2021 to 2024
$2.1MLeptin in HIV associated vascular diseasesR01HL147639 · NHLBI · AUGUSTA UNIVERSITY · PI BELIN DE CHANTEMELE, ERIC J · 2020 to 2023
$2.0MMitochondria Dynamics Protein Drp1 in ROS Signaling, Endothelial Metabolism and AngiogenesisR01HL160014 · NHLBI · AUGUSTA UNIVERSITY · PI USHIO-FUKAI, MASUKO · 2021 to 2024
$2.0MAldosterone Contribution to Leptin-mediated Hypertension in Obese FemalesR01HL130301 · NHLBI · AUGUSTA UNIVERSITY · PI BELIN DE CHANTEMELE, ERIC J · 2016 to 2020
$1.9MProtein Disulfide Isomerase as Novel Redox Sensor in VEGF SignalingR01HL135584 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI USHIO-FUKAI, MASUKO · 2017 to 2020
$1.5MSUMOylation of Cu transport protein Atox1 in AtherosclerosisI01BX001232 · VA · JESSE BROWN VA MEDICAL CENTER · PI TOHRU FUKAI · 2012 to 2026
–American Heart Association-American Stroke Association 17POST33660754BLRD VA I01 BX001232NHLBI NIH HHS R01 HL116976NHLBI NIH HHS R01 HL130301NHLBI NIH HHS R01 HL133613NHLBI NIH HHS R01 HL135584NHLBI NIH HHS R01 HL147159NHLBI NIH HHS R01 HL147550NHLBI NIH HHS R01 HL147639NHLBI NIH HHS R01 HL155265NHLBI NIH HHS R01 HL160014
Abstract
Reactive oxygen species (ROS;
Indexed as
Cardiovascular DiseasesHomeostasisHumansMetabolic Networks and PathwaysNADPReactive Nitrogen SpeciesReactive Oxygen SpeciesSignal TransductionNADPReactive Nitrogen SpeciesReactive Oxygen Speciesmetabolismoxidative stressreactive nitrogen speciesreactive oxygen speciesredox signaling
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.