ArticlePhysics and imaging in radiation oncology2021
Cone beam computed tomography for dose calculation quality assurance for magnetic resonance-only radiotherapy.
Article in Physics and imaging in radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Dose differences between patients treated with MR-only, CT-only, or MR-CT fusion radiotherapy for prostate cancer.The British journal of radiology · 2025Article
- Brain MR-only workflow in clinical practice: A comparison among generators for quality assurance and patient positioning.Journal of applied clinical medical physics · 2025Article
- Results of 2023 survey on the use of synthetic computed tomography for magnetic resonance Imaging-only radiotherapy: Current status and future steps.Physics and imaging in radiation oncology · 2024Article
- Patient-specific quality assurance strategies for synthetic computed tomography in magnetic resonance-only radiotherapy of the abdomen.Physics and imaging in radiation oncology · 2023Article
- Cone beam computed tomography image guidance within a magnetic resonance imaging-only planning workflow.Physics and imaging in radiation oncology · 2023Article
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Authors and funding
6 authors.
Funding
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Abstract
background and purposeMagnetic Resonance (MR)-only prostate radiotherapy using synthetic Computed Tomography (sCT) algorithms with high dose accuracy has been clinically implemented. MR images can suffer from geometric distortions so Quality Assurance (QA) using an independent, geometrically accurate, image could be required. The first-fraction Cone Beam CT (CBCT) has demonstrated potential but has not been evaluated in a clinical MR-only pathway. This study evaluated the clinical use of CBCT for dose accuracy QA of MR-only radiotherapy. MATERIALS AND
methodsA total of 49 patients treated with MR-only prostate radiotherapy were divided into two cohorts. Cohort 1 (20 patients) received a back-up CT, whilst Cohort 2 (29 patients) did not. All patients were planned using the sCT and received daily CBCT imaging with MR-CBCT soft-tissue matching. Each CBCT was calibrated using a patient-specific stepwise Hounsfield Units-to-mass density curve. The treatment plan was recalculated on the first-fraction CBCT using the clinically applied soft-tissue match and the doses compared. For Cohort 1 the sCT was rigidly registered to the back-up CT, the plan recalculated and doses compared.
resultsMean sCT-CBCT dose difference across both cohorts was
conclusionsCBCT-based dose accuracy QA for MR-only radiotherapy appears clinically feasible. There was a small systematic sCT-CBCT dose difference implying asymmetric tolerances of [
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