Evidence map›Paper›PMID 33898623›Full record

ArticleBioMed research international2021

Antiangiogenic Effect of Platelet P2Y

Xiaoli Wang, Huan Zhao, Naiquan Yang, Yue Jin, Jianguo Chen

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Retracted: Antiangiogenic Effect of Platelet P2YBioMed research international · 2024
    Article
  2. Article
4 · The record

Corrections and comments

  • Retraction · 2024-03-20Computer-Aided Content or Computer-Generated Content · Concerns/Issues about Data · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Unreliable Results and/or Conclusions ·
  • Retracted
5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiaoli WangSchool of Medicine, Jiangsu University, Zhenjiang 212013, China.
Huan ZhaoDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China.
Naiquan YangDepartment of Cardiology, Huai'an Second People's Hospital Affiliated to Xuzhou Medical University, Huai'an 223002, China.ORCID https://orcid.org/0000-0001-9291-742X
Yue JinClinical Laboratory, Huai'an Second People's Hospital Affiliated to Xuzhou Medical University, Huai'an 223002, China.
Jianguo ChenClinical Laboratory, People's Hospital Affiliated to Jiangsu University, Zhenjiang 212002, China.ORCID https://orcid.org/0000-0002-1600-8766
Jiangsu University · CNXuzhou Medical College · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostischemic inflammation induces angiogenesis, while platelet P2Y

methodsLaser Doppler perfusion imaging and capillary density measurement were used for angiogenesis quantified. Immunofluorescence was used to detect the level of CD31. The mice muscle was harvested for enzyme-linked immunosorbent (ELISA) assay of interleukin- (IL) 10 activity and Western blot determination of vascular endothelial growth factor (VEGF) production.

resultsIschemic hindlimb angiogenesis was sharply decreased in IL-10

conclusionThe study underscores that the effect of ticagrelor antiangiogenic function is related with the higher IL-10 expression.

Indexed as

Angiogenesis Inducing AgentsAnimalsCapillariesHindlimbInterleukin-10IschemiaMaleMiceMice, Inbred C57BLMusclesNeovascularization, PhysiologicPerfusionPlatelet Aggregation InhibitorsPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y12TicagrelorAngiogenesis Inducing AgentsInterleukin-10Platelet Aggregation InhibitorsPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y12TicagrelorVascular Endothelial Growth Factors

Identifiers

PMID33898623
PMCPMC8052144
OpenAlexW3154644411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.