Evidence map›Paper›PMID 33898621›Full record

ArticleERJ open research2021

Dyspnoea and symptom burden in mild-moderate COPD: the Canadian Cohort Obstructive Lung Disease Study.

Mathew Cherian, Dennis Jensen, Wan C Tan, Sara Mursleen, Emma C Goodall, Gilbert A Nadeau, Amnah M Awan, Darcy D Marciniuk, Brandie L Walker, Shawn D Aaron and 7 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A Multi-Specialty Delphi Consensus on Assessing and Managing Cardiopulmonary Risk in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2024
    Article
  10. Physical Activity and Symptom Burden in COPD: The Canadian Obstructive Lung Disease Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2023
    Article
  11. Canadian family physician Medecin de famille canadien · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 1 country.

Mathew CherianDivision of Respiratory Medicine, Dept of Medicine, McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0001-5843-3886
Dennis JensenClinical Exercise and Respiratory Physiology Laboratory, Dept of Kinesiology and Physical Education, Faculty of Education, McGill University, Montréal, QC, Canada.
Wan C TanCentre for Heart Lung Innovation, Dept of Medicine, University of British Columbia, Vancouver, BC, Canada.
Sara MursleenGSK, Mississauga, ON, Canada.
Emma C GoodallGSK, Mississauga, ON, Canada.
Gilbert A NadeauGSK, Mississauga, ON, Canada.
Amnah M AwanGSK, Mississauga, ON, Canada.
Darcy D MarciniukRespiratory Research Centre, University of Saskatchewan, Saskatoon, SK, Canada.
Brandie L WalkerDivision of Respirology, Dept of Medicine, University of Calgary, Calgary, AB, Canada.
Shawn D AaronThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Denis E O'DonnellDept of Medicine/Physiology, Queens University, Kingston, ON, Canada.ORCID https://orcid.org/0000-0001-7593-2433
Kenneth R ChapmanAsthma and Airway Centre, University Health Network and University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-2498-9859
François MaltaisInstitut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, QC, Canada.
Paul HernandezFaculty of Medicine, Division of Respirology, Dalhousie University, Halifax, NS, Canada.
Don D SinCentre for Heart Lung Innovation, Dept of Medicine, University of British Columbia, Vancouver, BC, Canada.
Andrea BenedettiDepts of Medicine and of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.
Jean BourbeauDivision of Respiratory Medicine, Dept of Medicine, McGill University Health Centre, Montreal, QC, Canada.ORCID https://orcid.org/0000-0002-7649-038X
GlaxoSmithKline (Canada) · CAMcGill University Health Centre · CAUniversity of British Columbia · CADalhousie University · CAInstitut universitaire de cardiologie et de pneumologie de Québec · CAMcGill University · CAOttawa Hospital · CAQueen's University · CAUniversity Health Network · CAUniversity of Calgary · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies assessing dyspnoea and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD) have focussed on patients in clinical settings, not the general population. The aim of this analysis was to compare the prevalence and severity of dyspnoea and impaired HRQoL in individuals with and without COPD from the general population, focussing on mild-moderate COPD. Analysis of the 3-year Canadian Cohort Obstructive Lung Disease (CanCOLD) study included four subgroups: mild COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) 1); moderate COPD (GOLD 2); non-COPD smokers; and non-COPD never-smokers. The primary outcome was dyspnoea (Medical Research Council (MRC) scale), and the secondary outcome was HRQoL (COPD Assessment Test (CAT) score; Saint George's Respiratory Questionnaire (SGRQ) score). Subgroups were analysed by sex, physician-diagnosed COPD status and exacerbations. 1443 participants (mild COPD (n=397); moderate COPD (n=262(; smokers (n=449) and never-smokers (n=335)) were studied. People with mild COPD were more likely to report more severe dyspnoea (MRC 2

Identifiers

PMID33898621
PMCPMC8053913
OpenAlexW3121830630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.