Evidence map›Paper›PMID 33898446›Full record

ArticleFrontiers in cell and developmental biology2021

LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.

Li-Ming Dong, Xi-Ling Zhang, Ming-Huan Mao, Yan-Pei Li, Xi-Yan Zhang, Dong-Wei Xue, Yi-Li Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. PCMT1 as a prognostic marker in breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  4. Review
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  8. Characterization of the mScientific reports · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li-Ming DongDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Xi-Ling ZhangDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Ming-Huan MaoDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Yan-Pei LiDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Xi-Yan ZhangDepartment of General Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Dong-Wei XueDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
Yi-Li LiuDepartment of Urologic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang, China.
China Medical University · CNFourth Affiliated Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer has easy recurrence characteristics, but its occurrence and development mechanism are still unclear. Non-coding RNA is a kind of RNA that exists widely and cannot be translated into proteins, which has played a key role in the regulation of biological functions of tumor cells. However, the regulation mechanism of non-coding RNA on bladder tumors is not fully understood. By microarray analysis and database analysis, we found that LINC00511 was significantly highly expressed in bladder cancer. The expressions of LINC00511, miR-143-3p, and PCMT in bladder cancer tissues and cells were detected by quantitative reverse transcription-polymerase chain reaction. The relationship between the expressions of miR-143-3p and PCMT1 and the clinicopathological parameters of the tumor was analyzed. The proliferation and invasion of bladder cancer cells were detected by MTT assay and Transwell assay. The expression levels of E-cadherin and vimentin in bladder cancer cells were detected by Western blot. Cell apoptosis was detected by flow cytometry.

Indexed as

apoptosisbladder cancerinvasionLINC00511PCMT1

Identifiers

PMID33898446
PMCPMC8063617
OpenAlexW3153848218

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.