ArticleGerms2021
Microbial profile, antimicrobial resistance, and molecular characterization of diabetic foot infections in a university hospital.
Article in Germs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Prevalence of multidrug-resistant bacterial infections in diabetic foot ulcers: A meta-analysis.International wound journal · 2024Pooled it
- In Vitro Antibacterial Effect of Probiotics Against Bacterial Isolates from Diabetic Foot Ulcers in Ain Shams University Hospitals.Probiotics and antimicrobial proteins · 2026Article
- Diospyros kaki L. (persimmon) as a potential antibiofilm agent against Acinetobacter pittii, Acinetobacter baumannii, and Pseudomonas aeruginosa isolated from diabetic foot patients.World journal of microbiology & biotechnology · 2025Article
- Multifaceted Antibiotic Resistance in Diabetic Foot Infections: A Systematic Review.Microorganisms · 2025Review
- Molecular characterization of resistance and biofilm genes of ESKAPE pathogens isolated from clinical samples: examination of the effect of boric acid on biofilm ability by cell culture method.BMC microbiology · 2025Article
- Prospective Observational Study of Microbiology of Infected Diabetic Foot Ulcers in a Tertiary-Care Hospital.Cureus · 2024Article
- Anaerobes in diabetic foot infections: pathophysiology, epidemiology, virulence, and management.Clinical microbiology reviews · 2024Review
- The Microbial Diversity and Antimicrobial Susceptibility Profile Underlying Diabetic Foot Osteomyelitis: A Retrospective Study Conducted in North Queensland, Australia.Foot & ankle orthopaedics · 2024Article
- Diabetes-related lower limb wounds: Antibiotic susceptibility pattern and biofilm formation.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024Article
- Microbiological Species and Antibiotic Resistance in Diabetic and Nondiabetic Lower Extremity Wounds: A Comparative Cross-Sectional Study.The international journal of lower extremity wounds · 2024Article
- Transcriptomic fingerprint of bacterial infection in lower extremity ulcers.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022Article
- Prevalence of Extended-Spectrum β-Lactamase and Carbapenemase Producers of Gram-Negative Bacteria, and Methicillin-ResistantInfection and drug resistance · 2022Article
- Bacterial isolates from diabetic foot ulcers and their antimicrobial resistance profile from selected hospitals in Addis Ababa, Ethiopia.Frontiers in endocrinology · 2022Article
- Bacterial profile and antimicrobial resistance patterns of infected diabetic foot ulcers in low- and middle-income countries: a systematic review and meta‑analysis.Therapeutic advances in infectious diseaseReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDiabetic foot infections (DFIs) are among the most severe complications of diabetes. The aim of this study was to determine the etiological pathogens of DFIs in different Wagner's and IDSA/IWGDF grades, and to assess their antimicrobial susceptibility pattern together with molecular characterization of antibiotic resistance genes.
methodsA prospective study was conducted on 120 DFI patients at Main Alexandria University Hospital, Egypt. The aerobic and anaerobic etiological pathogens were determined using semi-quantitative culture and PCR respectively. The antimicrobial susceptibility pattern was done according to Clinical Laboratory Standards Institute guidelines. Detection of carbapenemases and class-1 integron genes was carried out by polymerase chain reaction (PCR).
resultsA total of 178 (124 aerobic, 54 anaerobic) pathogens were identified from patients with DFI, with an average of 1.82 isolates/subject. Among aerobic pathogens, Gram-negative predominated (98/124; 79%), of which
conclusionsMultidrug and extensively drug resistant Gram-negative bacteria were the dominant pathogens among all DFI severity grades. However, the proportion of Gram-positive bacteria decreased with the severity of infection. The clinical role of our relatively high rate of anaerobes should be investigated. The results found in this study could be beneficial for designing future empiric antimicrobial protocols in relation to the severity of DFIs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.