Evidence map›Paper›PMID 33898180›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Rationally Programming Nanomaterials with DNA for Biomedical Applications.

Liangcan He, Jing Mu, Oleg Gang, Xiaoyuan Chen

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Mini Review On: The Roles of DNA Nanomaterials in Phototherapy.International journal of nanomedicine · 2025
    Review
  8. Review
  9. Scaling up of a Self-Confined Catalytic Hybridization Circuit for Robust microRNA Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Current Trends of Raman Spectroscopy in Clinic Settings: Opportunities and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liangcan HeYong Loo Lin School of Medicine and Faculty of Engineering National University of Singapore Singapore 117597 Singapore.
Jing MuInstitute of Precision Medicine Peking University Shenzhen Hospital Shenzhen 518036 China.
Oleg GangDepartment of Chemical Engineering and Department of Applied Physics and Applied Mathematics Columbia University New York NY 10027 USA.
Xiaoyuan ChenYong Loo Lin School of Medicine and Faculty of Engineering National University of Singapore Singapore 117597 Singapore.ORCID 0000-0002-9622-0870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA is not only a carrier of genetic information, but also a versatile structural tool for the engineering and self-assembling of nanostructures. In this regard, the DNA template has dramatically enhanced the scalability, programmability, and functionality of the self-assembled DNA nanostructures. These capabilities provide opportunities for a wide range of biomedical applications in biosensing, bioimaging, drug delivery, and disease therapy. In this review, the importance and advantages of DNA for programming and fabricating of DNA nanostructures are first highlighted. The recent progress in design and construction of DNA nanostructures are then summarized, including DNA conjugated nanoparticle systems, DNA-based clusters and extended organizations, and DNA origami-templated assemblies. An overview on biomedical applications of the self-assembled DNA nanostructures is provided. Finally, the conclusion and perspectives on the self-assembled DNA nanostructures are presented.

Indexed as

AnimalsBiomedical TechnologyDNAHumansMiceNanomedicineNanostructuresDNAbiomedical applicationsDNA conjugationDNA nanostructuresDNA origamidynamic clusters

Identifiers

PMID33898180
PMCPMC8061415

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.