Evidence map›Paper›PMID 33898178›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing.

Zifeng Yang, Rongkang Huang, Bingna Zheng, Wentai Guo, Chuangkun Li, Wenyi He, Yingqi Wei, Yang Du, Huaiming Wang, Dingcai Wu and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

  1. Robust Stitching Interface and Deep Learning Empowered Hydrogel Human-Machine Interface.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Review
  4. Sprayable Hydrogel Dressings in Wound-Healing Applications.Bioengineering (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zifeng YangDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Rongkang HuangDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Bingna ZhengPCFM Lab and GDHPRC Lab School of Chemistry Sun Yat-sen University Guangzhou 510275 P. R. China.
Wentai GuoDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Chuangkun LiDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Wenyi HePCFM Lab and GDHPRC Lab School of Chemistry Sun Yat-sen University Guangzhou 510275 P. R. China.
Yingqi WeiDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Yang DuDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Huaiming WangDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.
Dingcai WuPCFM Lab and GDHPRC Lab School of Chemistry Sun Yat-sen University Guangzhou 510275 P. R. China.ORCID 0000-0003-1396-0097
Hui WangDepartment of Colorectal Surgery The Sixth Affiliated Hospital, Sun Yat-sen University, Guangdong Institute of Gastroenterology Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases Guangzhou 510655 P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of wounds in special areas is challenging due to inevitable movements and difficult fixation. Common cotton gauze suffers from incomplete joint surface coverage, confinement of joint movement, lack of antibacterial function, and frequent replacements. Hydrogels have been considered as good candidates for wound dressing because of their good flexibility and biocompatibility. Nevertheless, the adhesive, mechanical, and antibacterial properties of conventional hydrogels are not satisfactory. Herein, cationic polyelectrolyte brushes grafted from bacterial cellulose (BC) nanofibers are introduced into polydopamine/polyacrylamide hydrogels. The 1D polymer brushes have rigid BC backbones to enhance mechanical property of hydrogels, realizing high tensile strength (21-51 kPa), large tensile strain (899-1047%), and ideal compressive property. Positively charged quaternary ammonium groups of tethered polymer brushes provide long-lasting antibacterial property to hydrogels and promote crawling and proliferation of negatively charged epidermis cells. Moreover, the hydrogels are rich in catechol groups and capable of adhering to various surfaces, meeting adhesive demand of large movement for special areas. With the above merits, the hydrogels demonstrate less inflammatory response and faster healing speed for in vivo wound healing on rats. Therefore, the multifunctional hydrogels show stable covering, little displacement, long-lasting antibacteria, and fast wound healing, demonstrating promise in wound dressing.

Indexed as

Bandages, HydrocolloidAdhesivenessAnimalsAnti-Bacterial AgentsBiocompatible MaterialsDisease Models, AnimalHydrogelsRatsTensile StrengthWound HealingAnti-Bacterial AgentsBiocompatible MaterialsHydrogelsadhesiveantibacterial dressingshydrogel dressingsstretchable materialswound healing

Identifiers

PMID33898178
PMCPMC8061386

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.