Evidence map›Paper›PMID 33898086›Full record

ArticleJournal of radiosurgery and SBRT2021

Robustness of single-isocenter multiple-metastasis stereotactic radiosurgery end-to-end testing across institutions.

Daniel Saenz, Niko Papanikolaou, Emmanouil Zoros, Evangelos Pappas, Michael Reiner, Lip Teck Chew, Hooi Yin Lim, Sam Hancock, Alex Nebelsky, Christopher Njeh and 1 more

Abstract read
In one paragraph

Article in Journal of radiosurgery and SBRT, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. HyperArcGels (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel SaenzUniversity of Texas Health Science Center, San Antonio, TX, USA.
Niko PapanikolaouUniversity of Texas Health Science Center, San Antonio, TX, USA.
Emmanouil ZorosNational and Kapodistrian University of Athens Medical School, Athens, Greece.
Evangelos PappasUniversity of West Attica, Athens, Greece.
Michael ReinerLudwig Maximilian University of Munich, Munich, Germany.
Lip Teck ChewFarrer Park Hospital, Farrer Park, Singapore.
Hooi Yin LimFarrer Park Hospital, Farrer Park, Singapore.
Sam HancockSoutheast Health, Cape Girardeau, Missouri, USA.
Alex NebelskyRambam Medical Center, Haifa, Israel.
Christopher NjehFranciscan Health, Indianapolis, Indiana, USA.
Georgios AnagnostopoulosGerman Oncology Center, Limassol, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accuracy of stereotactic radiosurgery (SRS) to multiple metastases with a single-isocenter using high definition dynamic radiosurgery (HDRS) was evaluated across institutions. An SRS plan was delivered at six HDRS-capable institutions to an anthropomorphic phantom consisting of point, film, and 3D-gel dosimeters. Direct dose comparison and gamma analysis were used to evaluate the accuracy. Point measurements averaged across institutions were within 1.2±0.5%. The average gamma passing rate in the film was 96.6±2.2% (3%/2 mm). For targets within 4 cm of the isocenter, the 3D dosimetric gel gamma passing rate averaged across institutions was >90% (3%/2 mm). The targeting accuracy of high definition dynamic radiosurgery assessed by geometrical offset of the center of dose distributions across multiple institutions in this study was within 1 mm for targets within 4 cm of isocenter. Across variations in clinical practice, comparable dosimetry and localization is possible with this treatment planning and delivery technique.

Indexed as

assurancedosimetryGelqualityradiosurgerystereotactic

Identifiers

PMID33898086
PMCPMC8055241

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.