Evidence map›Paper›PMID 33898051›Full record

ArticleNeuro-oncology practice2021

Understanding sleep disturbance in the context of malignant brain tumors: a qualitative analysis.

Megan S Jeon, Meera R Agar, Eng-Siew Koh, Anna K Nowak, Elizabeth J Hovey, Haryana M Dhillon

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07628647 (Pilot Study of the Living Well With Brain Cancer Intervention), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07628647 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Pilot Study of the Living Well With Brain Cancer Intervention

TypeinterventionalSponsorUniversity of Colorado, DenverRan2026 to 2027Enrolled64ConditionsBrain CancerArmsGroup Self-Management Sessions, Educational Materials Only
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Megan S JeonSouth Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.
Meera R AgarSouth Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.
Eng-Siew KohSouth Western Sydney Clinical School, University of New South Wales, Sydney, NSW, Australia.
Anna K NowakMedical School, QEII Medical Centre Unit, University of Western Australia, Crawley, WA, Australia.
Elizabeth J HoveyNelune Comprehensive Cancer Centre, Prince of Wales Hospital, Randwick, NSW, Australia.
Haryana M DhillonCentre for Medical Psychology & Evidence-Based Decision-Making, University of Sydney, Sydney, NSW, Australia.
Ingham Institute · AUPrince of Wales Hospital · AUSir Charles Gairdner Hospital · AUSouth Western Sydney Local Health District · AUUniversity of Sydney · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep is an important element in health-related quality of life of cancer patients and caregivers. This study aimed to explore the experience of sleep disturbance in people with malignant brain tumors (BT) and their family caregivers.

methodsParticipants were recruited from ambulatory neuro-oncology clinics. Semi-structured interviews were conducted with 24 patients (67% with high-grade gliomas) and 14 caregivers. Data were analyzed thematically using a framework synthesis.

resultsWe identified six themes relating to perceptions of the nature, impact, causal factors, and interventions for sleep disturbance, beliefs about sleep and impact, and personal coping strategies. Participants described their sleep disturbance in terms of insomnia symptoms; most commonly difficulties initiating and maintaining sleep. Participants had varied views on causal factors including the BT diagnosis and treatment and caregiver burden. However, excessive thinking and BT-related anxiety were evident in both patients and caregivers. The described impact on daytime functioning due to non-restful sleep and fatigue appeared to be significant and many participants needed daytime naps, although they understated the impact on individual functioning. Some participants were reluctant to seek help from clinicians for sleep disturbance due to previous experiences where sleep disturbance was overlooked, or because they held negative views toward pharmacological interventions. Participants reported various coping strategies, ranging from relaxation-promoting techniques to behaviors to distract thinking at night that may instead disturb sleep.

conclusionsPsychological factors contribute to sleep disturbance in patients with BT and caregivers. This population may benefit from information about sleep disturbance and interventions targeting anxiety.

Indexed as

brain tumorcaregiversgliomasleep disturbancesupportive care

Identifiers

PMID33898051
PMCPMC8049408
OpenAlexW3108695541

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.