Evidence map›Paper›PMID 33898046›Full record

ReviewNeuro-oncology practice2021

Cognitive impact of lower-grade gliomas and strategies for rehabilitation.

Christina Weyer-Jamora, Melissa S Brie, Tracy L Luks, Ellen M Smith, Steve E Braunstein, Javier E Villanueva-Meyer, Paige M Bracci, Susan Chang, Shawn L Hervey-Jumper, Jennie W Taylor

Open access · greenAbstract readReview
In one paragraph

Review in Neuro-oncology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Symptom network and latent profile analysis in patients after glioma surgery: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Observational
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  10. Review
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christina Weyer-JamoraDepartment of Neurological Surgery, University of California San Francisco.
Melissa S BrieDepartment of Neurological Surgery, University of California San Francisco.
Tracy L LuksDepartment of Radiology and Biomedical Imaging, University of California San Francisco.
Ellen M SmithDepartment of Neurological Surgery, University of California San Francisco.
Steve E BraunsteinDepartment of Radiation Oncology, University of California San Francisco.
Javier E Villanueva-MeyerDepartment of Radiology and Biomedical Imaging, University of California San Francisco.
Paige M BracciDepartment of Epidemiology and Biostatistics, University of California San Francisco.
Susan ChangDepartment of Neurological Surgery, University of California San Francisco.
Shawn L Hervey-JumperDepartment of Neurological Surgery, University of California San Francisco.
Jennie W TaylorDepartment of Neurological Surgery, University of California San Francisco.
University of California, San Francisco · USNeurological Surgery · USSan Francisco General Hospital · US

Funding

Intratumoral functional connectivity with implications on synaptogenesis and aphasia recovery in adult astrocytic WHO II-III gliomaK08NS110919 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HERVEY-JUMPER, SHAWN L. · 2019 to 2023
$1.0M
NINDS NIH HHS K08 NS110919
6 · The paper itself

Abstract

Outcomes for patients with lower-grade gliomas (LrGGs) continue to improve with advances in molecular characterization and treatment. However, cognitive sequela from the tumor and its treatment leave a significant impact on health-related quality of life for these patients. Several factors affect each patient's cognition, such as tumor location, treatment, medication, and comorbidities. However, impairments of processing speed, attention, concentration, working memory, and executive function are common across LrGG patients. Cognitive rehabilitation strategies, well established in traumatic brain injury and stroke populations, are based on neural plasticity and functional reorganization. Adapting these strategies for implementation in patients with brain tumors is an active area of research. This article provides an overview of cognitive domains commonly impaired in LrGG patients and evidence for the use of cognitive rehabilitation strategies to address these impairments with the goal of improving health-related quality of life in this patient population.

Indexed as

cognitive outcomescognitive rehabilitationlow-grade gliomaneurocognitive outcomesprimary brain tumor

Identifiers

PMID33898046
PMCPMC8049427
OpenAlexW3096212791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.