Evidence map›Paper›PMID 33897984›Full record

ArticleComputational and structural biotechnology journal2021

AMR-Diag: Neural network based genotype-to-phenotype prediction of resistance towards β-lactams in

Ekaterina Avershina, Priyanka Sharma, Arne M Taxt, Harpreet Singh, Stephan A Frye, Kolin Paul, Arti Kapil, Umaer Naseer, Punit Kaur, Rafi Ahmad

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
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  15. eMIC-AntiKP: Estimating minimum inhibitory concentrations of antibiotics towardsComputational and structural biotechnology journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Ekaterina AvershinaDepartment of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 22, 2317 Hamar, Norway.
Priyanka SharmaDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Arne M TaxtDepartment of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 22, 2317 Hamar, Norway.
Harpreet SinghInformatics, System and Research Management, Indian Council of Medical Research, New Delhi, India.
Stephan A FryeDepartment of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, PB 4956, Nydalen, 0424 Oslo, Norway.
Kolin PaulDepartment of Computer Science & Engineering, IIT Delhi, New Delhi, India.
Arti KapilDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Umaer NaseerDepartment of Zoonotic, Food- and Waterborne Infections, 0213 Oslo, Norwegian Institute of Public Health, Oslo, Norway.
Punit KaurDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Rafi AhmadDepartment of Biotechnology, Inland Norway University of Applied Sciences, Holsetgata 22, 2317 Hamar, Norway.
All India Institute of Medical Sciences · INOslo University Hospital · NOUniversity of Inland Norway · NOIndian Council of Medical Research · INIndian Institute of Technology Delhi · INNorwegian Institute of Public Health · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance poses a major threat to public health. More effective ways of the antibiotic prescription are needed to delay the spread of antibiotic resistance. Employment of sequencing technologies coupled with the use of trained neural network algorithms for genotype-to-phenotype prediction will reduce the time needed for antibiotic susceptibility profile identification from days to hours. In this work, we have sequenced and phenotypically characterized 171 clinical isolates of

Indexed as

Antibiotic resistanceAntibiotic susceptibility testingBacterial infectionCarbapenemasesColistinE. coliExtended spectrum β-lactamasesGenotype to phenotypeK. pneumoniaeMachine learningNeural networksRapid diagnostics

Identifiers

PMID33897984
PMCPMC8060595
OpenAlexW3149549685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.