Evidence map›Paper›PMID 33897882›Full record

ArticleTheranostics2021

MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer.

Qiji Li, Min Wang, Yanqing Hu, Ensi Zhao, Jun Li, Liangliang Ren, Meng Wang, Yuandong Xu, Qian Liang, Di Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Unveiling SNX10: a key player in bladder cancer progression.Translational andrology and urology · 2025
    Article
  14. Malevolent alliance of MYBL2Journal for immunotherapy of cancer · 2025
    Article
  15. Article
  16. Article
  17. Epigenetic silencing ofOncology reports · 2025
    Article
  18. Article
  19. Review
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Qiji LiDepartment of Orthopaedic Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Min WangDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Yanqing HuDepartment of Orthopaedic Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Ensi ZhaoDepartment of Orthopaedic Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Jun LiDepartment of Urology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Liangliang RenClinical Experimental Center, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529030, China.
Meng WangDepartment of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Yuandong XuDepartment of Urology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Qian LiangScientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Di ZhangScientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Yingrong LaiDepartment of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Shaoyu LiuDepartment of Orthopaedic Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Xinsheng PengDepartment of Orthopaedic Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Chengming ZhuScientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
Liping YeScientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, China.
The Seventh Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CNJiangmen Central Hospital · CNSun Yat-sen University Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Androgen AntagonistsCastrationCell Cycle ProteinsCell Line, TumorGene Expression Regulation, NeoplasticHippo Signaling PathwayHumansMaleNeoplasm Recurrence, LocalPC-3 CellsPrognosisProstatic Neoplasms, Castration-ResistantProtein Serine-Threonine KinasesProto-Oncogene MasReceptors, AndrogenSignal TransductionAndrogen AntagonistsCell Cycle ProteinsMAS1 protein, humanMYBL2 protein, humanProtein Serine-Threonine KinasesProto-Oncogene MasReceptors, AndrogenTrans-ActivatorsTranscription FactorsYY1AP1 protein, humanCastration resistanceHippo-YAP pathwayMYBL2.Prostate cancerRhoA activation

Identifiers

PMID33897882
PMCPMC8058714
OpenAlexW3153652407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.