Evidence map›Paper›PMID 33897875›Full record

ArticleTheranostics2021

Nodal-induced L1CAM/CXCR4 subpopulation sustains tumor growth and metastasis in colorectal cancer derived organoids.

Donatella Delle Cave, Xavier Hernando-Momblona, Marta Sevillano, Gabriella Minchiotti, Enza Lonardo

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
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  4. Disruption of the Nucleolin-CXCR4 interaction by the DNA aptamer HY-4 halts colorectal cancer metastasis.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Novel Therapeutic Approaches for Colorectal Cancer Treatment.International journal of molecular sciences · 2024
    Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donatella Delle CaveInstitute of Genetics and Biophysics'Adriano Buzzati-Traverso' (IGB), CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
Xavier Hernando-MomblonaInstitute for Research in Biomedicine Barcelona (IRB), Barcelona, Spain.
Marta SevillanoInstitute for Research in Biomedicine Barcelona (IRB), Barcelona, Spain.
Gabriella MinchiottiInstitute of Genetics and Biophysics'Adriano Buzzati-Traverso' (IGB), CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
Enza LonardoInstitute of Genetics and Biophysics'Adriano Buzzati-Traverso' (IGB), CNR, Via Pietro Castellino 111, 80131 Naples, Italy.
Institute for Research in Biomedicine · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorCell MovementCell ProliferationColorectal NeoplasmsHumansMiceNeoplasm MetastasisNeural Cell Adhesion Molecule L1Nodal ProteinOrganoidsReceptors, CXCR4Signal TransductionTumor MicroenvironmentCXCR4 protein, humanL1CAM protein, humanNeural Cell Adhesion Molecule L1Nodal ProteinNODAL protein, humanReceptors, CXCR4CD171)colorectal cancer (CRC), organoids, transforming growth factor (TGF)-β signaling, L1 cell adhesion molecule (L1CAM

Identifiers

PMID33897875
PMCPMC8058729
OpenAlexW3156165614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.