Evidence map›Paper›PMID 33897805›Full record

ArticleNano today2021

Recent advances in porous nanostructures for cancer theranostics.

Jinping Wang, Beilu Zhang, Jingyu Sun, Wei Hu, Hongjun Wang

Abstract read
In one paragraph

Article in Nano today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. The emergence of nanoporous materials in lung cancer therapy.Science and technology of advanced materials · 2022
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinping WangDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey, 07030, United States.
Beilu ZhangDepartment of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, New Jersey, 07030, United States.
Jingyu SunDepartment of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, New Jersey, 07030, United States.
Wei HuDepartment of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, New Jersey, 07030, United States.
Hongjun WangDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey, 07030, United States.

Funding

Micro- and nanofiber enabled biomimetic periosteum for bone repair and reconstructionR01AR067859 · NIAMS · UNIVERSITY OF ROCHESTER · PI WANG, HONGJUN, ZHANG, XINPING · 2016 to 2020
$2.7M
NIAMS NIH HHS R01 AR067859
6 · The paper itself

Abstract

Porous nanomaterials with high surface area, tunable porosity, and large mesopores have recently received particular attention in cancer therapy and imaging. Introduction of additional pores to nanostructures not only endows the tunability of optoelectronic and optical features optimal for tumor treatment, but also modulates the loading capacity and controlled release of therapeutic agents. In recognition, increasing efforts have been made to fabricate various porous nanomaterials and explore their potentials in oncology applications. Thus, a systematic and comprehensive summary is necessary to overview the recent progress, especially in last ten years, on the development of various mesoporous nanomaterials for cancer treatment as theranostic agents. While outlining their individual synthetic mechanisms after a brief introduction of the structures and properties of porous nanomaterials, the current review highlighted the representative applications of three main categories of porous nanostructures (organic, inorganic, and organic-inorganic nanomaterials). In each category, the synthesis, representative examples, and interactions with tumors were further detailed. The review was concluded with deliberations on the key challenges and future outlooks of porous nanostructures in cancer theranostics.

Indexed as

BioimagingCancer therapyDrug deliveryMesoporous nanomaterialTheranostics

Identifiers

PMID33897805
PMCPMC8059603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.