ArticleJournal of contemporary brachytherapy2021
Intra-operative 3D hologram support with mixed reality technique based on CT-MRI fusion images: operation guidance for brain brachytherapy.
Article in Journal of contemporary brachytherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Evaluation of augmented reality for interstitial brachytherapy optimisation: a prospective phantom-based study protocol and preliminary results.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026Article
- Transforming Global Neurosurgical Education Through Mixed Reality Development: A 12-Year Bibliometric Analysis.Cureus · 2025Review
- Virtual reality-guided simulation of brachytherapy: Two case reports.Journal of contemporary brachytherapy · 2025Article
- Augmented reality in brachytherapy: A narrative review.Journal of contemporary brachytherapy · 2024Review
- Advances and Innovations in Ablative Head and Neck Oncologic Surgery Using Mixed Reality Technologies in Personalized Medicine.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe study investigated whether intra-operative 3D hologram, a computer graphics model of the brain, with mixed reality (MR) technique based on computed tomography-magnetic resonance imaging (CT-MRI) fusion images could be helpful during brachytherapy for brain metastasis. MATERIAL AND
methodsA patient with relapsed brain metastasis was reported. Pre-operative CT and MRI image fusion was performed, with software developed by our center and the Chinese University of Hong Kong. 3D polygon data segmented from pre-operative CT-MRI fusion images were registered into HoloLens (Microsoft Corporation, Redmond, WA, USA).
resultsInterventional surgeons could share the same hologram and move the hologram from their respective angles, while wearing the HoloLens without any monitors. The intra-operative hologram offered good visualization of the skull, tumor location, and main vessels around the tumor during brain brachytherapy of a patient with brain metastasis. The interventional surgeons could easily compare the patient's actual anatomy with the hologram before and during the brain brachytherapy procedure. D
conclusionsThis initial experience suggests that the use of the intra-operative hologram with MR technique based on CT-MRI fusion images helped in brachytherapy guidance. Further research is needed to explore the potential of this approach in neuro-navigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.