Evidence map›Paper›PMID 33897792›Full record

ArticleJournal of contemporary brachytherapy2021

Individualized mould-based high-dose-rate brachytherapy for perinasal skin tumors: technique evaluation from a dosimetric point of view.

Christian Scherf, Jörg Licher, Christina Mletzko, Martin Trommel, Nikolaos Tselis, Georgios Chatzikonstantinou, Markus Diefenhardt, Claus Rödel, Janett Köhn, Ulla Ramm

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trends in radiation oncology between 2015 and 2022: report from a German university radio-oncology department.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  2. Article
  3. Advantages of 3D printed patient-individual moulds in brachytherapy for facial skin cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  4. Article
  5. Is model-based dose calculation based on cone-beam computed tomography suitable for adaptive treatment planning in brachytherapy?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christian ScherfDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Jörg LicherDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Christina MletzkoDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Martin TrommelDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Nikolaos TselisDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Georgios ChatzikonstantinouDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Markus DiefenhardtDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Claus RödelDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Janett KöhnDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.
Ulla RammDepartment of Radiation Oncology, University Hospital, Goethe University, Frankfurt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDosimetric treatment planning evaluations concerning patient-adapted moulds for iridium-192 high-dose-rate brachytherapy are presented in this report. MATERIAL AND

methodsSix patients with perinasal skin tumors were treated with individual moulds made of biocompatible epithetic materials with embedded plastic applicators. Treatment plans were optimized with regard to clinical requirements, and dose was calculated using standard water-based TG-43 formalism. In addition, retrospective material-dependent collapsed cone calculations according to TG-186 protocol were evaluated to quantify the limitations of TG-43 protocol for this superficial brachytherapy technique.

resultsThe dose-volume parameters D

conclusionsHDR contact BT with individual moulds is a safe modality for routine treatment of perinasal skin tumors. The technique provides good target coverage and OARs' protection, while being robust against small variances in mould material density. Model-based dose calculations (TG-186) should complement TG-43 dose calculations for verification purpose and quality improvement.

Indexed as

brachytherapyindividual mouldsperinasal skin cancerTG-186TG-43

Identifiers

PMID33897792
PMCPMC8060955

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.