Evidence map›Paper›PMID 33897701›Full record

ArticleFrontiers in immunology2021

Identification of Prognostic Genes in the Tumor Microenvironment of Hepatocellular Carcinoma.

Shixin Xiang, Jing Li, Jing Shen, Yueshui Zhao, Xu Wu, Mingxing Li, Xiao Yang, Parham Jabbarzadeh Kaboli, Fukuan Du, Yuan Zheng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. The Prognostic and Biological Value of PGF-Based H&E Pathomics in Hepatocellular Carcinoma.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  3. Adhesion G protein-coupled receptors.Pharmacological reviews · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Multifaceted Roles of Guanylate-Binding Proteins in Cancer.International journal of molecular sciences · 2025
    Review
  12. Inhibiting neddylation: A new strategy for tumor therapy.Journal of pharmaceutical analysis · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Shixin XiangLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Jing LiDepartment of Oncology and Hematology, Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, China.
Jing ShenLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Yueshui ZhaoLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Xu WuLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Mingxing LiLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Xiao YangLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Parham Jabbarzadeh KaboliLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Fukuan DuLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Yuan ZhengNeijiang Health and Health Vocational College, Neijiang, China.
Qinglian WenDepartment of Oncology, Affiliated Hospital of Southwest Medical University, Luzhou, China.
Chi Hin ChoLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
Tao YiSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China.
Zhangang XiaoLaboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, China.
First Affiliated Hospital of Sichuan Medical University · CNSouthwest Medical University · CNAffiliated Hospital of Southwest Medical University · CNHong Kong Baptist University · HKNeijiang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorCarcinoma, HepatocellularComputational BiologyDatabases, GeneticGene Expression ProfilingGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateLiver NeoplasmsPrognosisReproducibility of ResultsTumor MicroenvironmentBiomarkers, TumorESTIMATE algorithmHepatocellular carcinomaPrognosisTCGAtumor microenvironment

Identifiers

PMID33897701
PMCPMC8059369
OpenAlexW3146358078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.